Iontophoresis promotes percutaneous absorption of l-ascorbic acid in rat skin

Background: Percutaneous absorption of ascorbic acid is limited by its impermeability and instability. Objective: We attempted to improve the percutaneous absorption of ascorbic acid by use of iontophoresis after topical application of ascorbic acid. Methods: Radioactivities extracted from epidermal...

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Veröffentlicht in:	Journal of dermatological science 2003-09, Vol.32 (3), p.217-222
Hauptverfasser:	Ebihara, Mutsuhito, Akiyama, Minoru, Ohnishi, Yoshihiro, Tajima, Shingo, Komata, Ki-ichi, Mitsui, Yukio
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Topical Animals Ascorbic acid Ascorbic Acid - administration & dosage Ascorbic Acid - pharmacokinetics Autoradiography Biological Transport Cosmetology Dermis - metabolism Epidermis - metabolism Iontophoresis Male Percutaneous absorption Rats Skin - metabolism Skin Absorption Skin aging Time Factors
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