Sequence-ion studies in peptides: the generation of C″ ions
The mechanism for the formation of C"-type ions from protonated peptides, produced under conditions of fast-atom bombardment and collisional activation was investigated. Comparison of the tandem mass spectra of the [M + H]+ ions of a model peptide and the corresponding [Md + D]+ ions, in which...
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| Veröffentlicht in: | Rapid communications in mass spectrometry 1993-03, Vol.7 (3), p.241-244 |
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| container_title | Rapid communications in mass spectrometry |
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| creator | VAN DONGEN, W. D DE KOSTER, C. G HEERMA, W HAVERKAMP, J |
| description | The mechanism for the formation of C"-type ions from protonated peptides, produced under conditions of fast-atom bombardment and collisional activation was investigated. Comparison of the tandem mass spectra of the [M + H]+ ions of a model peptide and the corresponding [Md + D]+ ions, in which all exchangeable hydrogens are replaced with deuterium, revealed that neither the carboxylic hydrogen nor a hydrogen from a nitrogen atom is involved in the process of migration of a hydrogen which leads to the formation of C"n-type ions. The most feasible position from which the transferred hydrogen originates is that at the first C-atom in the side-chain of the adjacent amino acid. |
| doi_str_mv | 10.1002/rcm.1290070315 |
| format | Article |
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The most feasible position from which the transferred hydrogen originates is that at the first C-atom in the side-chain of the adjacent amino acid.</description><subject>Amino Acid Sequence</subject><subject>Chemistry</subject><subject>Deuterium</subject><subject>Exact sciences and technology</subject><subject>Hydrogen</subject><subject>Ions</subject><subject>Mass spectrometry</subject><subject>Mass Spectrometry - methods</subject><subject>Molecular Sequence Data</subject><subject>Oligopeptides - chemistry</subject><subject>Organic chemistry</subject><subject>Peptides - chemistry</subject><subject>Reactivity and mechanisms</subject><subject>Spectrometry, Mass, Fast Atom Bombardment</subject><issn>0951-4198</issn><issn>1097-0231</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1993</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9zztLxEAQB_BFlPM8be2EFGKXc2efWcFCDl9wYKHWYTeZ1ZW8zCaFnd_Jb-QnMWKwmoH_b4YZQo6BroFSdt4X9RqYoVRTDnKHLIEanVLGYZcsqZGQCjDZPjmI8Y1SAMnogiwykYEUfEkuH_F9xKbANLRNEoexDBiT0CQddkMoMV4kwysmL9hgb4df0_pk8_35lUx9PCR73lYRj-a6Is8310-bu3T7cHu_udqmHSg9pK4sHAcOykjlLOOmdMYLX3h0XnpujfIMpKbMZMild1yWPmNOgpq485yvyNnf3q5vp3PjkNchFlhVtsF2jLmehrXWYoInMxxdjWXe9aG2_Uc-_zvlp3NuY2Er39umCPGfCSWYUIz_ANtGZKY</recordid><startdate>19930301</startdate><enddate>19930301</enddate><creator>VAN DONGEN, W. 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| ispartof | Rapid communications in mass spectrometry, 1993-03, Vol.7 (3), p.241-244 |
| issn | 0951-4198 1097-0231 |
| language | eng |
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| source | MEDLINE; Access via Wiley Online Library |
| subjects | Amino Acid Sequence Chemistry Deuterium Exact sciences and technology Hydrogen Ions Mass spectrometry Mass Spectrometry - methods Molecular Sequence Data Oligopeptides - chemistry Organic chemistry Peptides - chemistry Reactivity and mechanisms Spectrometry, Mass, Fast Atom Bombardment |
| title | Sequence-ion studies in peptides: the generation of C″ ions |
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