The effect of quercetin on the mRNA expression of different antioxidant enzymes in hepatoma cells

The flavonol quercetin shows a wide range of effects in biological systems. We investigated whether quercetin exerts its proposed antioxidant properties via the antioxidant enzyme system. Quercetin in a concentration range from 5 to 100 microM decreased manganese superoxide dismutase, glutathione pe...

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Veröffentlicht in:	Archives of toxicology 2003-09, Vol.77 (9), p.506-510
Hauptverfasser:	RÖHRDANZ, Elke, BITTNER, Achim, TRAN-THI, Quynh-Hoa, KAHL, Regine
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antioxidants Antioxidants - metabolism Biological and medical sciences Blotting, Northern Catalase - biosynthesis Catalase - genetics Cell metabolism, cell oxidation Cell physiology Down-Regulation Enzymes Fundamental and applied biological sciences. Psychology Glutathione Peroxidase Lipid Peroxidation - drug effects Liver Neoplasms, Experimental Molecular and cellular biology Nutrition Quercetin - pharmacology Rats RNA, Messenger - biosynthesis Rodents Superoxide Dismutase - biosynthesis Superoxide Dismutase - genetics Tumor Cells, Cultured
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