A comparison of microtubule assembly in brain extracts from young and old rats

Microtubule assembly was examined in the high-speed supernatant from homogenates of young (2–4 months old) and old (more than 24 months old) rat brains and significant age-related differences in microtubule assembly were found in the absence of exogenous GTP. In extracts from young brains, the incre...

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Veröffentlicht in:	Brain research. Molecular brain research. 1993-04, Vol.18 (1), p.100-106
Hauptverfasser:	Qian, A., Burton, P.R., Himes, R.H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Factors Aging Animals Biochemistry and metabolism Biological and medical sciences Brain - metabolism Brain - ultrastructure Central nervous system Fundamental and applied biological sciences. Psychology GTP GTP Phosphohydrolases - metabolism GTPase activity Guanosine Triphosphate - physiology Kinetics Male Microscopy, Electron Microtubule assembly Microtubules - metabolism Microtubules - ultrastructure Nerve Tissue Proteins - metabolism Polymers Rats Rats, Inbred F344 Tissue Extracts Tubulin Tubulin - metabolism Vertebrates: nervous system and sense organs
Online-Zugang:	Volltext
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