Connexin-36 Contributes to Control Function of Insulin-producing Cells

Connexin-36 (Cx36) is a gap junction protein expressed by the insulin-producing β-cells. We investigated the contribution of this protein in normal β-cell function by using a viral gene transfer approach to alter Cx36 content in the insulin-producing line of INS-1E cells and rat pancreatic islets. T...

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Veröffentlicht in:	The Journal of biological chemistry 2003-09, Vol.278 (39), p.37690-37697
Hauptverfasser:	Le Gurun, Sabine, Martin, David, Formenton, Andrea, Maechler, Pierre, Caille, Dorothée, Waeber, Gérard, Meda, Paolo, Haefliger, Jacques-Antoine
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenoviridae - genetics Amino Acid Sequence Animals Calcium - metabolism Cell Line Connexins - physiology Gap Junction delta-2 Protein Insulin - analysis Insulin - metabolism Insulin Secretion Islets of Langerhans - physiology Molecular Sequence Data Rats
Online-Zugang:	Volltext
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