Comparative activity of the anti-convulsants oxcarbazepine, carbamazepine, lamotrigine and gabapentin in a model of neuropathic pain in the rat and guinea-pig

Anti-epileptic drugs (AEDs) are increasingly used for the treatment of neuropathic pain. Oxcarbazepine is a recently introduced AED that is effective in treating epilepsy and has an improved side-effect profile compared to existing therapies. Here we have examined the effect of oxcarbazepine and oth...

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Veröffentlicht in:	Pain (Amsterdam) 2003-09, Vol.105 (1), p.355-362
Hauptverfasser:	Fox, Alyson, Gentry, Clive, Patel, Sadhana, Kesingland, Adam, Bevan, Stuart
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetates - pharmacology Amines Analgesics Animals Anticonvulsants - pharmacology Biological and medical sciences Carbamazepine - analogs & derivatives Carbamazepine - pharmacology Cyclohexanecarboxylic Acids Gabapentin gamma-Aminobutyric Acid Guinea Pigs Hyperalgesia - etiology Hyperalgesia - physiopathology Lamotrigine Male Medical sciences Neuralgia - etiology Neuralgia - physiopathology Neuropathic pain Neuropharmacology Oxcarbazepine Pain Threshold Pharmacology. Drug treatments Pressure Rats Rats, Wistar Sciatic Nerve - injuries Touch Triazines - pharmacology Wounds and Injuries - complications
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