Prospective analysis of urokinase in the treatment of catheter sepsis in pediatric hematology-oncology patients

Use of right atrial catheters (RACs) in children with cancer improves the comfort and efficacy of therapy. However, catheter-related infections are responsible for significant morbidity leading to the removal of approximately 20% of implanted RACs. Sepsis has been linked to thrombus and fibrin sheat...

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Veröffentlicht in:	Journal of pediatric surgery 1993-03, Vol.28 (3), p.350-357
Hauptverfasser:	Jones, Gary R., Konsler, Gwen K., Dunaway, Rose P., Lacey, Stuart R., Azizkhan, Richard G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Age Factors Anti-Bacterial Agents - therapeutic use Bacteremia - drug therapy Bacteremia - etiology Catheterization, Central Venous - adverse effects Catheters, Indwelling - adverse effects Child Child, Preschool Drug Therapy, Combination Fungemia - drug therapy Fungemia - etiology Heart Atria Humans Infant Infant, Newborn Leukemia - therapy Neoplasms - therapy Prospective Studies Time Factors Urokinase-Type Plasminogen Activator - therapeutic use
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