Troponin I Gene Expression During Human Cardiac Development and in End-Stage Heart Failure

Recent reports have demonstrated the presence of two isoforms of troponin I in the human fetal heart, namely, cardiac troponin I and slow skeletal muscle troponin I. Structural and physiological considerations indicate that these isoforms would confer differing contractile properties on the myocardi...

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Veröffentlicht in:	Circulation research 1993-05, Vol.72 (5), p.932-938
Hauptverfasser:	Sasse, Sabine, Brand, Nigel J, Kyprianou, Philip, Dhoot, Gurtej K, Wade, Robert, Arai, Masashi, Periasamy, Muthu, Yacoub, Magdi H, Barton, Paul J.R
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Biological and medical sciences Cardiac Output, Low - genetics Cardiac Output, Low - metabolism Child Child, Preschool Embryonic and Fetal Development Fetus - physiology Fundamental and applied biological sciences. Psychology Gene Expression Heart Heart - embryology Heart - growth & development Humans Infant Infant, Newborn Isomerism Middle Aged Muscles - metabolism Myocardium - metabolism RNA, Messenger - metabolism Troponin - genetics Troponin - metabolism Troponin I Vertebrates: cardiovascular system
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