Prevention of Thromboembolic Disease by Vitamin E
To the Editor: Since the early 1950s, Alton Ochsner has repeatedly advocated the administration of alpha-tocopherol (vitamin E) to prevent postoperative thromboembolism. 1 2 3 4 5 6 As late as 1968, he said, "for 15 years I have used alpha tocopherol routinely in the treatment of patients who h...
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| Veröffentlicht in: | The New England journal of medicine 1981-07, Vol.305 (3), p.173-174 |
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| container_title | The New England journal of medicine |
| container_volume | 305 |
| creator | Kanofsky, J D Kanofsky, P B |
| description | To the Editor:
Since the early 1950s, Alton Ochsner has repeatedly advocated the administration of alpha-tocopherol (vitamin E) to prevent postoperative thromboembolism.
1
2
3
4
5
6
As late as 1968, he said, "for 15 years I have used alpha tocopherol routinely in the treatment of patients who have been subjected to trauma of any magnitude. None of these patients have had pulmonary embolism."
6
The tocopherol-calcium regimen consists of 200 to 600 IU of alpha-tocopherol per day, administered intramuscularly or by mouth, beginning no later than the day of surgery and continuing through the postoperative period. Concurrently, 10 ml of a 10 per cent calcium . . . |
| doi_str_mv | 10.1056/NEJM198107163050322 |
| format | Article |
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Since the early 1950s, Alton Ochsner has repeatedly advocated the administration of alpha-tocopherol (vitamin E) to prevent postoperative thromboembolism.
1
2
3
4
5
6
As late as 1968, he said, "for 15 years I have used alpha tocopherol routinely in the treatment of patients who have been subjected to trauma of any magnitude. None of these patients have had pulmonary embolism."
6
The tocopherol-calcium regimen consists of 200 to 600 IU of alpha-tocopherol per day, administered intramuscularly or by mouth, beginning no later than the day of surgery and continuing through the postoperative period. Concurrently, 10 ml of a 10 per cent calcium . . .</description><identifier>ISSN: 0028-4793</identifier><identifier>EISSN: 1533-4406</identifier><identifier>DOI: 10.1056/NEJM198107163050322</identifier><identifier>PMID: 7242594</identifier><language>eng</language><publisher>United States: Massachusetts Medical Society</publisher><subject>Administration, Oral ; Humans ; Injections, Intramuscular ; Thromboembolism - prevention & control ; Vitamin E - administration & dosage ; Vitamin E - therapeutic use</subject><ispartof>The New England journal of medicine, 1981-07, Vol.305 (3), p.173-174</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c336t-e1a296c20a1ce3c7f01c8282808e9aa00ddd84ecca3d29a7885743121c375ddb2</citedby><cites>FETCH-LOGICAL-c336t-e1a296c20a1ce3c7f01c8282808e9aa00ddd84ecca3d29a7885743121c375ddb2</cites></display><links><openurl>$$Topenurl_article</openurl><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>776</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/7242594$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kanofsky, J D</creatorcontrib><creatorcontrib>Kanofsky, P B</creatorcontrib><title>Prevention of Thromboembolic Disease by Vitamin E</title><title>The New England journal of medicine</title><addtitle>N Engl J Med</addtitle><description>To the Editor:
Since the early 1950s, Alton Ochsner has repeatedly advocated the administration of alpha-tocopherol (vitamin E) to prevent postoperative thromboembolism.
1
2
3
4
5
6
As late as 1968, he said, "for 15 years I have used alpha tocopherol routinely in the treatment of patients who have been subjected to trauma of any magnitude. None of these patients have had pulmonary embolism."
6
The tocopherol-calcium regimen consists of 200 to 600 IU of alpha-tocopherol per day, administered intramuscularly or by mouth, beginning no later than the day of surgery and continuing through the postoperative period. Concurrently, 10 ml of a 10 per cent calcium . . .</description><subject>Administration, Oral</subject><subject>Humans</subject><subject>Injections, Intramuscular</subject><subject>Thromboembolism - prevention & control</subject><subject>Vitamin E - administration & dosage</subject><subject>Vitamin E - therapeutic use</subject><issn>0028-4793</issn><issn>1533-4406</issn><fulltext>false</fulltext><rsrctype>article</rsrctype><creationdate>1981</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kEtLw0AUhQdRaq3-AhGyciPRO4_MYym1vqiPRXUbJpMbTMlkaiYV-u-NtLgS7-VyF-ecb3EIOaVwSSGTV8-zxydqNAVFJYcMOGN7ZEwzzlMhQO6TMQDTqVCGH5KjGJcwDBVmREaKCZYZMSb0tcMvbPs6tEmoksVHF3wRcLimdslNHdFGTIpN8l731tdtMjsmB5VtIp7s_oS83c4W0_t0_nL3ML2ep45z2adILTPSMbDUIXeqAuo0GxY0GmsByrLUAp2zvGTGKq0zJThl1HGVlWXBJuR8y1114XONsc99HR02jW0xrGOuMmmASzkY-dbouhBjh1W-6mpvu01OIf8pKv-jqCF1tsOvC4_lb2bXzKBfbHXvY97i0v9L-wbF4232</recordid><startdate>19810716</startdate><enddate>19810716</enddate><creator>Kanofsky, J D</creator><creator>Kanofsky, P B</creator><general>Massachusetts Medical Society</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19810716</creationdate><title>Prevention of Thromboembolic Disease by Vitamin E</title><author>Kanofsky, J D ; Kanofsky, P B</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c336t-e1a296c20a1ce3c7f01c8282808e9aa00ddd84ecca3d29a7885743121c375ddb2</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1981</creationdate><topic>Administration, Oral</topic><topic>Humans</topic><topic>Injections, Intramuscular</topic><topic>Thromboembolism - prevention & control</topic><topic>Vitamin E - administration & dosage</topic><topic>Vitamin E - therapeutic use</topic><toplevel>peer_reviewed</toplevel><creatorcontrib>Kanofsky, J D</creatorcontrib><creatorcontrib>Kanofsky, P B</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The New England journal of medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>no_fulltext</fulltext></delivery><addata><au>Kanofsky, J D</au><au>Kanofsky, P B</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Prevention of Thromboembolic Disease by Vitamin E</atitle><jtitle>The New England journal of medicine</jtitle><addtitle>N Engl J Med</addtitle><date>1981-07-16</date><risdate>1981</risdate><volume>305</volume><issue>3</issue><spage>173</spage><epage>174</epage><pages>173-174</pages><issn>0028-4793</issn><eissn>1533-4406</eissn><abstract>To the Editor:
Since the early 1950s, Alton Ochsner has repeatedly advocated the administration of alpha-tocopherol (vitamin E) to prevent postoperative thromboembolism.
1
2
3
4
5
6
As late as 1968, he said, "for 15 years I have used alpha tocopherol routinely in the treatment of patients who have been subjected to trauma of any magnitude. None of these patients have had pulmonary embolism."
6
The tocopherol-calcium regimen consists of 200 to 600 IU of alpha-tocopherol per day, administered intramuscularly or by mouth, beginning no later than the day of surgery and continuing through the postoperative period. Concurrently, 10 ml of a 10 per cent calcium . . .</abstract><cop>United States</cop><pub>Massachusetts Medical Society</pub><pmid>7242594</pmid><doi>10.1056/NEJM198107163050322</doi><tpages>2</tpages></addata></record> |
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| ispartof | The New England journal of medicine, 1981-07, Vol.305 (3), p.173-174 |
| issn | 0028-4793 1533-4406 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_75690366 |
| source | MEDLINE |
| subjects | Administration, Oral Humans Injections, Intramuscular Thromboembolism - prevention & control Vitamin E - administration & dosage Vitamin E - therapeutic use |
| title | Prevention of Thromboembolic Disease by Vitamin E |
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