Mechanisms of Action of the Antimycotic Imidazoles

The mechanism of the antifungal action of the imidazole antimycotics, miconazole ano clotrimazole, on Saccharomyces cerevisiae was explored. When grown aerobically both drugs were fungistatic at low concentrations and fungicidal at high concentrations. When grown anaerobically the fungistatic effect...

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Veröffentlicht in:	Journal of investigative dermatology 1981-06, Vol.76 (6), p.438-441
Hauptverfasser:	Sud, Inder Jit, Feingold, David S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Clotrimazole - pharmacology Dose-Response Relationship, Drug Ergosterol - analysis Ergosterol - antagonists & inhibitors Imidazoles - pharmacology Lanosterol - analysis Miconazole - pharmacology Microbial Sensitivity Tests Saccharomyces cerevisiae Saccharomyces cerevisiae - analysis Saccharomyces cerevisiae - drug effects
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