PHARMACOKINETICS OF FLUMAZENIL AND MIDAZOLAM

We have studied simultaneously the pharmaco-kinetics of flumazenil and midazolam in 12 healthy Chinese children, aged 5–9 yr, undergoing circumcision. Two hours before operation each patient received midazolam 0.5 mg kg-1 orally for pre-medication and 0.5 mg kg-1 i. v. during induction. Six minutes...

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Veröffentlicht in:	British journal of anaesthesia : BJA 1993-03, Vol.70 (3), p.286-292
Hauptverfasser:	JONES, R.D.M., CHAN, K., ROULSON, C.J., BROWN, A.G., SMITH, I.D., MYA, G.H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anaesthesia: paediatric Antagonists: flumazenil benzodiazepines: midazolam Biological and medical sciences Child Child, Preschool Circumcision, Male Flumazenil - pharmacokinetics Half-Life Humans Hypnotics Hypnotics. Sedatives Male Medical sciences Midazolam - pharmacokinetics Neuropharmacology Pharmacokinetics Pharmacology. Drug treatments Psychology. Psychoanalysis. Psychiatry Psychomotor Performance - drug effects Psychopharmacology Time Factors
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