HLA-A11 Epitope Loss Isolates of Epstein-Barr Virus from a Highly A11$^+$ Population

Cytotoxic T lymphocytes (CTLs) control viral infections by recognizing viral peptides presented by major histocompatibility complex (MHC) class I molecules. Human leukocyte antigen (HLA)-A11-restricted CTLs that recognize peptide residues 416 to 424 of the Epstein-Barr virus (EBV) nuclear antigen-4...

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Veröffentlicht in:	Science (American Association for the Advancement of Science) 1993-04, Vol.260 (5104), p.98-100
Hauptverfasser:	de Campos-Lima, Pedro-Otavio, Gavioli, Riccardo, Zhang, Qian-Jin, Wallace, Lesley E., Dolcetti, Riccardo, Rowe, Martin, Rickinson, Alan B., Masucci, Maria G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Africa Antibodies Antigenic determinants Antigenic determinants, haptens, artificial antigens Antigens Antigens, Viral - genetics Antigens, Viral - immunology B lymphocytes Biological and medical sciences Cell Line, Transformed Cell lines Cell Nucleus - immunology Cell Transformation, Viral DNA-Binding Proteins - genetics DNA-Binding Proteins - immunology Epitopes Epitopes - genetics Epitopes - immunology Epstein Barr virus infections Epstein-Barr virus Epstein-Barr Virus Nuclear Antigens European Continental Ancestry Group Fundamental and applied biological sciences. Psychology Fundamental immunology Gene Frequency Herpesvirus 4, Human - immunology HLA antigens HLA-A Antigens - genetics HLA-A Antigens - immunology HLA-A11 Antigen Humans Lymphocytes Molecular immunology Molecules New Guinea Point Mutation T-Lymphocytes, Cytotoxic - immunology Transfection Viruses
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