Neutrophil alloantibodies react with cytoplasmic antigens : a possible cause of false-positive indirect immunofluorescence assays for antibodies to neutrophil cytoplasmic antigens

Antibodies to neutrophil cytoplasmic antigens (ANCA) can be detected in patients with Wegener's granulomatosis and systemic vasculitis. During pregnancy or following transfusion, subjects sometimes produce alloantibodies to neutrophil antigens. If patient sera being tested for ANCA contain allo...

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Veröffentlicht in:	American journal of kidney diseases 1993-04, Vol.21 (4), p.368-373
Hauptverfasser:	STRONCEK, D. F, EGGING, M. S, EIBER, G. A, CLAY, M. E
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies, Antineutrophil Cytoplasmic Autoantibodies - blood Biological and medical sciences Cytoplasm - immunology False Positive Reactions Fluorescent Antibody Technique GPI-Linked Proteins Granulocytes Humans Immunophenotyping Investigative techniques, diagnostic techniques (general aspects) Isoantibodies - blood Isoantigens - immunology Medical sciences Membrane Glycoproteins - immunology Miscellaneous. Technology Neutrophils - immunology Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Receptors, Cell Surface
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