Strong expression of HDAC3 correlates with a poor prognosis in patients with adenocarcinoma of the lung

Inhibition of histone deacetylases (HDACs) is a promising new approach to the treatment of lung cancer therapy. The relation between HDAC3 expression and the clinicopathological characteristics of lung cancer is not well understood, however. We therefore addressed this issue in patients with adenoca...

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Veröffentlicht in:	Tumor biology 2010-10, Vol.31 (5), p.533-539
Hauptverfasser:	Minamiya, Yoshihiro, Ono, Takashi, Saito, Hajime, Takahashi, Naoko, Ito, Manabu, Motoyama, Satoru, Ogawa, Junichi
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - metabolism Adenocarcinoma - mortality Adenocarcinoma - pathology Biomarkers, Tumor - analysis Biomedical and Life Sciences Biomedicine Cancer Research Cellular biology Disease-Free Survival Female Gene expression Histone Deacetylases - biosynthesis Humans Immunohistochemistry Lung cancer Lung Neoplasms - metabolism Lung Neoplasms - mortality Lung Neoplasms - pathology Male Medical prognosis Middle Aged Neoplasm Staging Prognosis Proportional Hazards Models Research Article Reverse Transcriptase Polymerase Chain Reaction
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