Tenofovir and Entecavir Are the Most Effective Antiviral Agents for Chronic Hepatitis B: A Systematic Review and Bayesian Meta-analyses

Background & Aims The relative efficacies of licensed antiviral therapies for treatment-naive chronic hepatitis B (CHB) infection in randomized controlled trials have not been determined. We evaluated the relative efficacies of the first 12 months of CHB treatments. Methods Drugs evaluated were...

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Veröffentlicht in:	Gastroenterology (New York, N.Y. 1943) N.Y. 1943), 2010-10, Vol.139 (4), p.1218-1229.e5
Hauptverfasser:	Woo, Gloria, Tomlinson, George, Nishikawa, Yasunori, Kowgier, Matthew, Sherman, Morris, Wong, David K.H, Pham, Ba, Ungar, Wendy J, Einarson, Thomas R, Heathcote, E. Jenny, Krahn, Murray
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenine - analogs & derivatives Adenine - therapeutic use Antiviral Agents - administration & dosage Antiviral Agents - adverse effects Antiviral Agents - therapeutic use Bayesian Direct and Indirect Comparison Drug Therapy, Combination Gastroenterology and Hepatology Guanine - analogs & derivatives Guanine - therapeutic use Hepatitis B e Antigens - analysis Hepatitis B Virus (HBV) Hepatitis B, Chronic - drug therapy Humans Lamivudine - therapeutic use Meta-analysis Mixed Treatment Comparison (MTC) Organophosphonates - therapeutic use Tenofovir
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