Role of store-operated calcium entry in imperatorin-induced vasodilatation of rat small mesenteric artery

Store-operated Ca 2+ entry (SOCE) has recently been proposed to contribute to Ca 2+ influx in vascular smooth muscle cells (VSMCs). Imperatorin is known for its potent vasodilatory effects as a dietary furanocoumarin. The study was designed to examine the hypothesis that SOCE have a functional role...

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Veröffentlicht in:	European journal of pharmacology 2010-11, Vol.647 (1), p.126-131
Hauptverfasser:	Zhang, Yan, Wang, Qun Li, Zhan, Ying Zhuan, Duan, Hai Jie, Cao, Yan Jun, He, Lang Chong
Format:	Artikel
Sprache:	eng
Schlagworte:	Aniline Compounds - metabolism Animals Biological and medical sciences Calcium - metabolism Calcium - pharmacology Calcium Channels - drug effects Calcium Channels - metabolism Calcium Channels - physiology Calcium Signaling - drug effects Furocoumarins - metabolism Furocoumarins - pharmacology Imperatorin Ion Transport - drug effects Male Medical sciences Mesenteric Arteries - drug effects Mesenteric Arteries - metabolism Muscle, Smooth, Vascular - drug effects Muscle, Smooth, Vascular - metabolism Pharmacology. Drug treatments Rats Rats, Sprague-Dawley Store-operated Ca 2+ entry (SOCE) Vascular smooth muscle cells (VSMCs) Vasodilation - drug effects Vasodilation - physiology Vasodilator Agents - metabolism Vasodilator Agents - pharmacology Vasorelaxation Xanthenes - metabolism
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