High efficacy and low toxicity of short-course oral valganciclovir as pre-emptive therapy for hematopoietic stem cell transplant cytomegalovirus infection

BACKGROUND Cytomegalovirus (CMV) infection is a major infectious complication post-allogeneic hematopoietic stem cell transplantation (HSCT). CMV seropositivity in Eastern Mediterranean and certain Asian countries is reported to be close to 100%; hence, the need for effective pre-emptive treatment s...

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Veröffentlicht in:	Hematology/oncology and stem cell therapy 2010-07, Vol.3 (3), p.116-120
Hauptverfasser:	Saleh, A.J.M, Al Mohareb, Fahad, Al Rabiah, Fahad, Chaudhri, Naeem, Al Sharif, Fahad, Al Zahrani, Hazzaa, Mohamed, Said Yousuf, Patel, Moosa, Rasheed, Walid, Nurgat, Zubeir, Bakr, Mohammad, Ahmed, Shad, Zaidi, Syed, Nassar, Amr, Ibrahim, Khaled, Al Abdely, Hail, Aljurf, Mahmoud
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Adolescent Adult Antigens, Viral - blood Antiviral Agents - administration & dosage Antiviral Agents - adverse effects Antiviral Agents - therapeutic use Cytomegalovirus - drug effects Cytomegalovirus - immunology Cytomegalovirus Infections - drug therapy Cytomegalovirus Infections - etiology Drug Administration Schedule Female Ganciclovir - adverse effects Ganciclovir - analogs & derivatives Ganciclovir - therapeutic use Hematology, Oncology and Palliative Medicine Hematopoietic Stem Cell Transplantation - adverse effects Humans Kidney Diseases - chemically induced Male Middle Aged Neutropenia - chemically induced Treatment Outcome Young Adult
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