Elevated Stimulatory and Reduced Inhibitory G Protein α Subunits in Cerebellar Cortex of Patients with Dominantly Inherited Olivopontocerebellar Atrophy

: Although guanine nucleotide binding proteins (G proteins) are one of the critical components of signal transduction units for various membrane receptor‐mediated responses, little information is available regarding their status in brain of patients with neurodegenerative illnesses. We measured the...

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Veröffentlicht in:	Journal of neurochemistry 1993-05, Vol.60 (5), p.1816-1820
Hauptverfasser:	Kish, Stephen J., Young, L. Trevor, Li, Peter P., Siu, Kin Po, Robitaille, Yves, Ball, Melvyn J., Schut, Lawrence, Warsh, Jerry J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Cerebellar ataxia Cerebellar Cortex - metabolism Cerebellum Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Electrophoresis Female Genes, Dominant GTP-Binding Proteins - metabolism Guanine nucleotide binding proteins Humans Immunoblotting Male Medical sciences Middle Aged Neurology Olivopontocerebellar Atrophies - genetics Olivopontocerebellar Atrophies - metabolism Olivopontocerebellar atrophy Purkinje cell Reference Values
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