Emergency coronary angioplasty for acute myocardial infarction: Predictors of early occlusion of the infarct-related artery after balloon inflation

The factors responsible for early occlusion of the infarct vessel after emergency percutaneous transluminal coronary angioplasty (PTCA) were retrospectively examined in 191 patients with acute myocardial infarction. During the 24-hour period after the initial balloon inflation, 47 patients (25%) had...

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Veröffentlicht in:The American heart journal 1993-04, Vol.125 (4), p.931-938
Hauptverfasser: Shirotani, Manabu, Yui, Yoshiki, Hattori, Ryuichi, Morishita, Hiroshi, Kawai, Chuichi, Susawa, Takashi, Tamaki, Shun-ichi, Takahashi, Mamoru, Sakaguchi, Keiji
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container_end_page 938
container_issue 4
container_start_page 931
container_title The American heart journal
container_volume 125
creator Shirotani, Manabu
Yui, Yoshiki
Hattori, Ryuichi
Morishita, Hiroshi
Kawai, Chuichi
Susawa, Takashi
Tamaki, Shun-ichi
Takahashi, Mamoru
Sakaguchi, Keiji
description The factors responsible for early occlusion of the infarct vessel after emergency percutaneous transluminal coronary angioplasty (PTCA) were retrospectively examined in 191 patients with acute myocardial infarction. During the 24-hour period after the initial balloon inflation, 47 patients (25%) had occlusion of the vessel (occlusion group), whereas 144 did not (nonocclusion group). The former patients immediately underwent repeat PTCA, which was successful in 37. Univariate correlates of early occlusion were a shorter time interval between the onset of symptoms and PTCA (3.5 ± 2.2 vs 4.5 ± 2.9 hours, p = 0.025), right coronary artery involvement (53% vs 30%, p = 0.015), prior thrombolytic therapy (49% vs 32%, p = 0.035), and undersized inflation (43% vs 17%, p < 0.001). With multivariate analysis the three independent predictors were undersized inflation ( p = 0.011). Thus patients undergoing early PTCA and having right coronary artery involvement appear to be at greater risk of having early occlusion. Thrombolytic agents and undersized inflation may also play an important role in its development.
doi_str_mv 10.1016/0002-8703(93)90099-U
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subjects Aged
Angioplasty, Balloon, Coronary
Biological and medical sciences
Cardiology. Vascular system
Coronary Disease - etiology
Coronary heart disease
Emergency Medical Services
Female
Forecasting
Heart
Hemorrhage - etiology
Humans
Male
Medical sciences
Middle Aged
Multivariate Analysis
Myocardial Infarction - therapy
Postoperative Complications
Thrombolytic Therapy
Treatment Outcome
title Emergency coronary angioplasty for acute myocardial infarction: Predictors of early occlusion of the infarct-related artery after balloon inflation
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