Tumor necrosis factor-alpha induces circular forms of human immunodeficiency virus type-1 DNA in the persistently infected low-level expressing cell line, ACH-2

The low human immunodeficiency virus type-1 (HIV-1) expressing T-cell line, ACH-2, was used to investigate accumulation of the circular, extrachromosomal form of HIV DNA (HD) after tumor necrosis factor-alpha (TNF-α) induction. We chose the 2 long terminal repeat (LTR) circular form to analyze unint...

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Veröffentlicht in:	Virus research 1993-02, Vol.27 (2), p.113-118
Hauptverfasser:	Kitamura, Katsuhiko, Zaki, Sherif R., Greer, Patricia W., Sinha, Saswati D., Folks, Thomas M.
Format:	Artikel
Sprache:	eng
Schlagworte:	AIDS/HIV Biological and medical sciences Cell Line Circular HIV DNA by TNF-α DNA, Circular - biosynthesis DNA, Circular - genetics DNA, Viral - biosynthesis DNA, Viral - genetics Fundamental and applied biological sciences. Psychology HIV Infections - etiology HIV Long Terminal Repeat HIV-1 - drug effects HIV-1 - genetics HIV-1 - metabolism human immunodeficiency virus 1 Humans In situ hybridization Microbiology Polymerase chain reaction Replicative cycle, interference, host-virus relations, pathogenicity, miscellaneous strains Subcellular Fractions - metabolism Tumor Necrosis Factor-alpha - pharmacology Virology
Online-Zugang:	Volltext
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