Differential expression of Na,K-ATPase alpha and beta subunit isoforms at the blood-brain barrier and the choroid plexus

The relative levels of expression of Na,K-ATPase alpha and beta subunit isoforms were determined in rat cerebral microvessels, choroid plexus, and capillary-depleted brain homogenates by Western blot analysis. Three alpha (alpha 1, alpha 2, alpha 3) and two beta (beta 1, beta 2) subunits were detect...

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Veröffentlicht in:	The Journal of biological chemistry 1993-04, Vol.268 (11), p.8019-8025
Hauptverfasser:	Zlokovic, B V, Mackic, J B, Wang, L, McComb, J G, McDonough, A
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical, structural and metabolic biochemistry Animals Biological and medical sciences Blood-Brain Barrier Blotting, Western Brain - enzymology Cerebrovascular Circulation Choroid Plexus - enzymology Enzymes and enzyme inhibitors Fundamental and applied biological sciences. Psychology Hydrolases Isoenzymes - analysis Isoenzymes - biosynthesis Kinetics Macromolecular Substances Male Microcirculation - enzymology Muscle, Smooth, Vascular - enzymology Organ Specificity Rats Rats, Sprague-Dawley Sodium-Potassium-Exchanging ATPase - analysis Sodium-Potassium-Exchanging ATPase - biosynthesis
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