Lung albumin content after acid aspiration pulmonary injury
The effects of aspiration of saline and acid on lymph albumin and pulmonary albumin contents were studied. Two radiolabeled species of albumin were used, I 125-albumin was allowed to equilibrate while 131I-albumin was injected at Time 0 of the experiment. One percent of total injected albumin was fo...
Gespeichert in:
| Veröffentlicht in: | The Journal of surgical research 1981-03, Vol.30 (3), p.256-261 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 261 |
|---|---|
| container_issue | 3 |
| container_start_page | 256 |
| container_title | The Journal of surgical research |
| container_volume | 30 |
| creator | Stothert, Joseph C. Jean Weaver, L. James Carrico, C. |
| description | The effects of aspiration of saline and acid on lymph albumin and pulmonary albumin contents were studied. Two radiolabeled species of albumin were used, I
125-albumin was allowed to equilibrate while
131I-albumin was injected at Time 0 of the experiment. One percent of total injected albumin was found in the lung in the saline and control groups for both the equilibrated and non-equilibrated varieties of albumin. Seven percent of injected dose of
125I-albumin (equilibrated) was found in the lung after acid aspiration, while 16% of the nonequilibrated
131I-albumin was found. The rate of “wash in” of
131I-albumin was significantly increased in the lymph of acid aspirated animals as compared to controls. These data suggest that the previously demonstrated increase in microvascular permeability after acid aspiration results in an increase in extravascular pulmonary albumin. This effect should greatly alter the local osmotic gradient and result in altered fluid balance. |
| doi_str_mv | 10.1016/0022-4804(81)90157-8 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_75645706</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>0022480481901578</els_id><sourcerecordid>75645706</sourcerecordid><originalsourceid>FETCH-LOGICAL-c357t-71b7f6a7617b38b5195e37a091a4e444b9ff4bfeff5a4578837ed8ebb0a5d7833</originalsourceid><addsrcrecordid>eNp9kE9LxDAQxYMo67r6DRR6Ej1Uk03SSREEWfwHC170HJJ2IlnadE1aYb-9XXfx6GkY5r03Mz9Czhm9YZQVt5TO57lQVFwpdl1SJiFXB2TKaClzVQA_JNM_yTE5SWlFx74EPiETmHMKIKbkbjmEz8w0dmh9yKou9Bj6zLgeY2YqX2cmrX00ve9Cth6atgsmbjIfVkPcnJIjZ5qEZ_s6Ix9Pj--Ll3z59vy6eFjmFZfQ58AsuMJAwcByZSUrJXIwtGRGoBDCls4J69A5aYQEpThgrdBaamQNivMZudzlrmP3NWDqdetThU1jAnZD0iCL0UeLUSh2wip2KUV0eh19Ox6sGdVbZnoLRG-BaMX0LzOtRtvFPn-wLdZ_pj2kcX6_m-P45LfHqFPlMVRY-4hVr-vO_7_gB4qAev4</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>75645706</pqid></control><display><type>article</type><title>Lung albumin content after acid aspiration pulmonary injury</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><creator>Stothert, Joseph C. ; Jean Weaver, L. ; James Carrico, C.</creator><creatorcontrib>Stothert, Joseph C. ; Jean Weaver, L. ; James Carrico, C.</creatorcontrib><description>The effects of aspiration of saline and acid on lymph albumin and pulmonary albumin contents were studied. Two radiolabeled species of albumin were used, I
125-albumin was allowed to equilibrate while
131I-albumin was injected at Time 0 of the experiment. One percent of total injected albumin was found in the lung in the saline and control groups for both the equilibrated and non-equilibrated varieties of albumin. Seven percent of injected dose of
125I-albumin (equilibrated) was found in the lung after acid aspiration, while 16% of the nonequilibrated
131I-albumin was found. The rate of “wash in” of
131I-albumin was significantly increased in the lymph of acid aspirated animals as compared to controls. These data suggest that the previously demonstrated increase in microvascular permeability after acid aspiration results in an increase in extravascular pulmonary albumin. This effect should greatly alter the local osmotic gradient and result in altered fluid balance.</description><identifier>ISSN: 0022-4804</identifier><identifier>EISSN: 1095-8673</identifier><identifier>DOI: 10.1016/0022-4804(81)90157-8</identifier><identifier>PMID: 7230774</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Albumins ; Animals ; Capillary Permeability ; Cardiac Output ; Dogs ; Hydrochloric Acid - pharmacology ; Iodine Radioisotopes ; Lung - analysis ; Lung Injury ; Lymph - analysis ; Plasma - analysis ; Sodium Chloride - pharmacology ; Suction ; Time Factors</subject><ispartof>The Journal of surgical research, 1981-03, Vol.30 (3), p.256-261</ispartof><rights>1981</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c357t-71b7f6a7617b38b5195e37a091a4e444b9ff4bfeff5a4578837ed8ebb0a5d7833</citedby><cites>FETCH-LOGICAL-c357t-71b7f6a7617b38b5195e37a091a4e444b9ff4bfeff5a4578837ed8ebb0a5d7833</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/0022480481901578$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/7230774$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Stothert, Joseph C.</creatorcontrib><creatorcontrib>Jean Weaver, L.</creatorcontrib><creatorcontrib>James Carrico, C.</creatorcontrib><title>Lung albumin content after acid aspiration pulmonary injury</title><title>The Journal of surgical research</title><addtitle>J Surg Res</addtitle><description>The effects of aspiration of saline and acid on lymph albumin and pulmonary albumin contents were studied. Two radiolabeled species of albumin were used, I
125-albumin was allowed to equilibrate while
131I-albumin was injected at Time 0 of the experiment. One percent of total injected albumin was found in the lung in the saline and control groups for both the equilibrated and non-equilibrated varieties of albumin. Seven percent of injected dose of
125I-albumin (equilibrated) was found in the lung after acid aspiration, while 16% of the nonequilibrated
131I-albumin was found. The rate of “wash in” of
131I-albumin was significantly increased in the lymph of acid aspirated animals as compared to controls. These data suggest that the previously demonstrated increase in microvascular permeability after acid aspiration results in an increase in extravascular pulmonary albumin. This effect should greatly alter the local osmotic gradient and result in altered fluid balance.</description><subject>Albumins</subject><subject>Animals</subject><subject>Capillary Permeability</subject><subject>Cardiac Output</subject><subject>Dogs</subject><subject>Hydrochloric Acid - pharmacology</subject><subject>Iodine Radioisotopes</subject><subject>Lung - analysis</subject><subject>Lung Injury</subject><subject>Lymph - analysis</subject><subject>Plasma - analysis</subject><subject>Sodium Chloride - pharmacology</subject><subject>Suction</subject><subject>Time Factors</subject><issn>0022-4804</issn><issn>1095-8673</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1981</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE9LxDAQxYMo67r6DRR6Ej1Uk03SSREEWfwHC170HJJ2IlnadE1aYb-9XXfx6GkY5r03Mz9Czhm9YZQVt5TO57lQVFwpdl1SJiFXB2TKaClzVQA_JNM_yTE5SWlFx74EPiETmHMKIKbkbjmEz8w0dmh9yKou9Bj6zLgeY2YqX2cmrX00ve9Cth6atgsmbjIfVkPcnJIjZ5qEZ_s6Ix9Pj--Ll3z59vy6eFjmFZfQ58AsuMJAwcByZSUrJXIwtGRGoBDCls4J69A5aYQEpThgrdBaamQNivMZudzlrmP3NWDqdetThU1jAnZD0iCL0UeLUSh2wip2KUV0eh19Ox6sGdVbZnoLRG-BaMX0LzOtRtvFPn-wLdZ_pj2kcX6_m-P45LfHqFPlMVRY-4hVr-vO_7_gB4qAev4</recordid><startdate>198103</startdate><enddate>198103</enddate><creator>Stothert, Joseph C.</creator><creator>Jean Weaver, L.</creator><creator>James Carrico, C.</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>198103</creationdate><title>Lung albumin content after acid aspiration pulmonary injury</title><author>Stothert, Joseph C. ; Jean Weaver, L. ; James Carrico, C.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c357t-71b7f6a7617b38b5195e37a091a4e444b9ff4bfeff5a4578837ed8ebb0a5d7833</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1981</creationdate><topic>Albumins</topic><topic>Animals</topic><topic>Capillary Permeability</topic><topic>Cardiac Output</topic><topic>Dogs</topic><topic>Hydrochloric Acid - pharmacology</topic><topic>Iodine Radioisotopes</topic><topic>Lung - analysis</topic><topic>Lung Injury</topic><topic>Lymph - analysis</topic><topic>Plasma - analysis</topic><topic>Sodium Chloride - pharmacology</topic><topic>Suction</topic><topic>Time Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Stothert, Joseph C.</creatorcontrib><creatorcontrib>Jean Weaver, L.</creatorcontrib><creatorcontrib>James Carrico, C.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Journal of surgical research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Stothert, Joseph C.</au><au>Jean Weaver, L.</au><au>James Carrico, C.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Lung albumin content after acid aspiration pulmonary injury</atitle><jtitle>The Journal of surgical research</jtitle><addtitle>J Surg Res</addtitle><date>1981-03</date><risdate>1981</risdate><volume>30</volume><issue>3</issue><spage>256</spage><epage>261</epage><pages>256-261</pages><issn>0022-4804</issn><eissn>1095-8673</eissn><abstract>The effects of aspiration of saline and acid on lymph albumin and pulmonary albumin contents were studied. Two radiolabeled species of albumin were used, I
125-albumin was allowed to equilibrate while
131I-albumin was injected at Time 0 of the experiment. One percent of total injected albumin was found in the lung in the saline and control groups for both the equilibrated and non-equilibrated varieties of albumin. Seven percent of injected dose of
125I-albumin (equilibrated) was found in the lung after acid aspiration, while 16% of the nonequilibrated
131I-albumin was found. The rate of “wash in” of
131I-albumin was significantly increased in the lymph of acid aspirated animals as compared to controls. These data suggest that the previously demonstrated increase in microvascular permeability after acid aspiration results in an increase in extravascular pulmonary albumin. This effect should greatly alter the local osmotic gradient and result in altered fluid balance.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>7230774</pmid><doi>10.1016/0022-4804(81)90157-8</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0022-4804 |
| ispartof | The Journal of surgical research, 1981-03, Vol.30 (3), p.256-261 |
| issn | 0022-4804 1095-8673 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_75645706 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Albumins Animals Capillary Permeability Cardiac Output Dogs Hydrochloric Acid - pharmacology Iodine Radioisotopes Lung - analysis Lung Injury Lymph - analysis Plasma - analysis Sodium Chloride - pharmacology Suction Time Factors |
| title | Lung albumin content after acid aspiration pulmonary injury |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-30T04%3A34%3A01IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Lung%20albumin%20content%20after%20acid%20aspiration%20pulmonary%20injury&rft.jtitle=The%20Journal%20of%20surgical%20research&rft.au=Stothert,%20Joseph%20C.&rft.date=1981-03&rft.volume=30&rft.issue=3&rft.spage=256&rft.epage=261&rft.pages=256-261&rft.issn=0022-4804&rft.eissn=1095-8673&rft_id=info:doi/10.1016/0022-4804(81)90157-8&rft_dat=%3Cproquest_cross%3E75645706%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=75645706&rft_id=info:pmid/7230774&rft_els_id=0022480481901578&rfr_iscdi=true |