31P magnetic resonance spectroscopy in alzheimer's and pick's disease

—Previous studies have suggested a defect in phosphorus metabolism in Alzheimer's disease (AD) gray matter. We have studied phosphorus metabolites in both gray and white matter in autopsy specimens of nine subjects with late-stage AD, three with Pick's disease and seven age-matched control...

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Veröffentlicht in:	Neurobiology of aging 1993, Vol.14 (1), p.85-92
Hauptverfasser:	Smith, C.D., Gallenstein, L.G., Layton, W.J., Kryscio, R.J., Markesbery, W.R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Alzheimer Disease - metabolism Alzheimer Disease - pathology Alzheimer's disease Biological and medical sciences Brain - pathology Brain Chemistry - physiology Cerebral Cortex - pathology Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Dementia - metabolism Dementia - pathology Humans Magnetic Resonance Spectroscopy Male Medical sciences Middle Aged Neurofibrillary Tangles - physiology Neurology Organophosphorus Compounds - metabolism Phosphates - metabolism Phosphodiesters Phosphomonoester Phosphorus - metabolism Phosphorus Isotopes Phosphorus magnetic resonance spectroscopy Pick's disease
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