An improved synthesis of [ 125I] N-(diethylaminoethyl)-4-iodobenzamide: a potential ligand for imaging malignant melanoma

To improve the radiolabeling yield and the specific activity of [ 125I] N-(2- d iethyl a minoethyl)-4-iodo b enza-mide (DAB), the aryltributyltin precursor was synthesized from the N-(2-diethylaminoethyl)-4-bromobenzamide derivative by palladium catalyzed stannylation using bis(tributyltin). The rad...

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Veröffentlicht in:	International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology Nuclear medicine and biology, 1993, Vol.20 (1), p.75-79
Hauptverfasser:	John, C.S., Saga, T., Kinuya, S., Le, N., Jeong, J.M., Paik, C.H., Reba, R.C., Varma, V.M., McAfee, J.G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Benzamides - chemical synthesis Benzamides - pharmacokinetics Biological and medical sciences Contrast Media - chemical synthesis Contrast Media - pharmacokinetics Contrast media. Radiopharmaceuticals Humans Medical sciences Melanoma - diagnostic imaging Melanoma - pathology Mice Mice, Inbred BALB C Mice, Nude Pharmacology. Drug treatments Radionuclide Imaging Tissue Distribution Tumor Cells, Cultured
Online-Zugang:	Volltext
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