Application of synthetic phospho- and unphospho- peptides to identify phosphorylation sites in a subregion of the tau molecule, which is modified in Alzheimer's disease

Phospho‐ and unphospho‐ peptides were used to define the essential sequence for a tau epitope, which is recognized by Tau‐1 antibody and phosphorylated in Alzheimer's disease (AD). The epitope was mapped within the amino acid residues 192–199 of tau and was phosphorylated by the p34cdc2/p58cycl...

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