Receptor subtype that mediates the neuronal effects of angiotensin ii in the rat dorsal medulla

We have shown previously that many neurons in the caudal medial nucleus tractus solitarii (nTS) are excited by angiotensin (Ang) II. The selective Ang II receptor antagonists losartan (AT 1; DuP 753) and CGP 42112A or PD 123177 (AT 2) were used to evaluate the receptor subtype that mediates excitati...

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Veröffentlicht in:	Brain research bulletin 1993, Vol.31 (1), p.195-200
Hauptverfasser:	Barnes, Karen L., McQueeney, Allison J., Ferrario, Carlos M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiotensin II Angiotensin II - antagonists & inhibitors Angiotensin II - pharmacology Angiotensin Receptor Antagonists Animals Biological and medical sciences Biphenyl Compounds - pharmacology Central nervous system Central neurotransmission. Neuromudulation. Pathways and receptors CGP 42112A Electrophysiology Fundamental and applied biological sciences. Psychology Glutamates - pharmacology Glutamic Acid Imidazoles - pharmacology In vitro brain slice In Vitro Techniques L-glutamate Losartan Losartan potassium Medulla Oblongata - cytology Medulla Oblongata - drug effects Neuronal recording Neurons - drug effects Nucleus tractus solitarii Oligopeptides - pharmacology PD 123177 Rats Rats, Sprague-Dawley Receptors, Angiotensin - physiology Subtype-selective Ang II receptor antagonists Tetrazoles - pharmacology Vertebrates: nervous system and sense organs
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