Stereoselective features of (R)- and (S)-atenolol: Clinical pharmacological, pharmacokinetic, and radioligand binding studies

In a randomized, double‐blind, cross‐over study in 12 healthy volunteers, the effects of single oral doses of 100 mg rac‐atenolol were compared during exercise to those of equal amounts of the optically pure enantiomers, i.e., 50 mg (R)‐ and 50 mg (S)‐atenolol. The mean rate pressure product decreas...

Ausführliche Beschreibung