Effects of p-chlorophenylalanine and methysergide on the performance of a working memory task

The present study investigated the effects of serotonergic dysfunction on working memory. Therefore, the effects of inhibition of serotonin [5-hydroxytryptamine (5-HT)] synthesis induced by ( p-chlorophenylalamine ( p-CPA and pharmacological blockade of 5-HT receptors by methysergide on the performa...

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Veröffentlicht in:	Pharmacology, biochemistry and behavior biochemistry and behavior, 1993-02, Vol.44 (2), p.411-418
Hauptverfasser:	Jäkälä, Pekka, Sirviö, Jouni, Riekkinen, Paavo, Riekkinen, Paavo J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Brain Chemistry - drug effects Brain Chemistry - physiology Conditioning, Operant - drug effects Delayed nonmatching Drug toxicity and drugs side effects treatment Fenclonine - pharmacology Male Medical sciences Memory - drug effects Methysergide Methysergide - pharmacology Miscellaneous (drug allergy, mutagens, teratogens...) p-Chlorophenylalamine Pharmacology. Drug treatments Psychomotor Performance - drug effects Rat Rats Rats, Wistar Serotonergic system Serotonin - metabolism Serotonin - physiology Working memory
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