Biochemical investigations of biopsied brain tissue and autopsied organs from a patient with pyroglutamic acidemia (5-oxoprolinemia)

Biochemical investigations have been carried out in autopsied tissues from a patient with pyroglutamic acidemia who died recently from thrombo-embolism. Very low activities of glutathione synthetase and a high content of pyroglutamate were found in all tissues examined. Especially high levels of pyr...

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Veröffentlicht in:	Clinica chimica acta 1981-04, Vol.111 (2), p.219-228
Hauptverfasser:	Marstein, S., Jellum, E., Nesbakken, R., Perry, T.L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Amino Acids - metabolism Brain - metabolism Glutathione - metabolism Glutathione Synthase - metabolism Humans Male Nervous System Diseases - metabolism Nervous System Diseases - pathology Pyrrolidinones - blood Pyrrolidonecarboxylic Acid - blood Pyrrolidonecarboxylic Acid - metabolism
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