Peritoneal Transfer During Maximal Hyperosmotic Ultrafiltration in the Rat
Peritoneal transfer parameters were estimated in rats (n=24) while maximal net ultrafiltration rate (nUFR) was achieved with 15% dextrose dialysis solution (1,153 mOsm/kg) and compared with those obtained with 0.37% dextrose solution (301 mOsm/kg). Experiments were carried out with dialysis solution...
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| Veröffentlicht in: | ASAIO journal (1992) 1993-01, Vol.39 (1), p.66-70 |
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| container_title | ASAIO journal (1992) |
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| creator | Grzegorzewska, Alicja E Moore, Harold L Chen, Tzen W Nolph, Karl D |
| description | Peritoneal transfer parameters were estimated in rats (n=24) while maximal net ultrafiltration rate (nUFR) was achieved with 15% dextrose dialysis solution (1,153 mOsm/kg) and compared with those obtained with 0.37% dextrose solution (301 mOsm/kg). Experiments were carried out with dialysis solutions of pH ?6.5 and ? 7.6, respectively, for 15% dextrose dialysis solution and 0.37% dextrose solution. Increases in both convective and diffusive transfer resulted in more than 70% greater peritoneal clearances of urea, potassium, and phosphate with hyperosmotic solutions at both pH values. Protein removal was increased only with a hyperosmotic solution of pH ? 6.5 compared with isosmotic conditions at the same pH. Results support the hypothesis that increased peritoneal transfer parameters under hyperosmotic conditions depend not only upon enhanced convection but also on factors promoting diffusive transfer |
| doi_str_mv | 10.1097/00002480-199339010-00015 |
| format | Article |
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Experiments were carried out with dialysis solutions of pH ?6.5 and ? 7.6, respectively, for 15% dextrose dialysis solution and 0.37% dextrose solution. Increases in both convective and diffusive transfer resulted in more than 70% greater peritoneal clearances of urea, potassium, and phosphate with hyperosmotic solutions at both pH values. Protein removal was increased only with a hyperosmotic solution of pH ? 6.5 compared with isosmotic conditions at the same pH. 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Experiments were carried out with dialysis solutions of pH ?6.5 and ? 7.6, respectively, for 15% dextrose dialysis solution and 0.37% dextrose solution. Increases in both convective and diffusive transfer resulted in more than 70% greater peritoneal clearances of urea, potassium, and phosphate with hyperosmotic solutions at both pH values. Protein removal was increased only with a hyperosmotic solution of pH ? 6.5 compared with isosmotic conditions at the same pH. Results support the hypothesis that increased peritoneal transfer parameters under hyperosmotic conditions depend not only upon enhanced convection but also on factors promoting diffusive transfer</description><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</subject><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>Data Interpretation, Statistical</subject><subject>Dialysis Solutions</subject><subject>Diffusion</subject><subject>Disease Models, Animal</subject><subject>Emergency and intensive care: renal failure. Dialysis management</subject><subject>Glucose</subject><subject>Hydrogen-Ion Concentration</subject><subject>Intensive care medicine</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Osmolar Concentration</subject><subject>Peritoneal Dialysis</subject><subject>Rats</subject><subject>Rats, Sprague-Dawley</subject><subject>Space life sciences</subject><subject>Ultrafiltration</subject><issn>1058-2916</issn><issn>1538-943X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1993</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVkUtPxCAQgInR-P4JJj0Yb1WmA205mvWdNRqzm3gjtKUu2m1XoFn997Ju3UQOQGa-YeCDkAjoOVCRXdAwEpbTGIRAFBRoHCLAt8g-cMxjwfB1O-wpz-NEQLpHDpx7XxGIsEt2c4Yizdk-eXjW1viu1aqJJla1rtY2uuqtad-iR_Vl5iF-973QtnPzzpsymjbeqtqsZm-6NjJt5Gc6elH-iOzUqnH6eFgPyfTmejK6i8dPt_ejy3FcIhM8zmqa64qrirGMl6hRZGlZpSzhFFlNRcUhUUihAA55yrKKplAVACrTSVFgjYfkbH3uwnafvXZezo0rddOoVne9kxnnImMAAczXYBlu76yu5cKGB9lvCVSuNMo_jXKjUf5qDKUnQ4--mOtqUzh4C_nTIa9cqZo6mCuN22BMJAgoAsbW2LJrvLbuo-mX2spZsO1n8t8nht50-ET8Acb_iQY</recordid><startdate>199301</startdate><enddate>199301</enddate><creator>Grzegorzewska, Alicja E</creator><creator>Moore, Harold L</creator><creator>Chen, Tzen W</creator><creator>Nolph, Karl D</creator><general>Lippincott-Raven Publishers</general><general>Lippincott</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>199301</creationdate><title>Peritoneal Transfer During Maximal Hyperosmotic Ultrafiltration in the Rat</title><author>Grzegorzewska, Alicja E ; Moore, Harold L ; Chen, Tzen W ; Nolph, Karl D</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3495-7f08ed5ad4475c3e3976cd6425034f09d512a301b1518647d061db11a7e2bb3f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1993</creationdate><topic>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</topic><topic>Animals</topic><topic>Biological and medical sciences</topic><topic>Data Interpretation, Statistical</topic><topic>Dialysis Solutions</topic><topic>Diffusion</topic><topic>Disease Models, Animal</topic><topic>Emergency and intensive care: renal failure. Dialysis management</topic><topic>Glucose</topic><topic>Hydrogen-Ion Concentration</topic><topic>Intensive care medicine</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Osmolar Concentration</topic><topic>Peritoneal Dialysis</topic><topic>Rats</topic><topic>Rats, Sprague-Dawley</topic><topic>Space life sciences</topic><topic>Ultrafiltration</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Grzegorzewska, Alicja E</creatorcontrib><creatorcontrib>Moore, Harold L</creatorcontrib><creatorcontrib>Chen, Tzen W</creatorcontrib><creatorcontrib>Nolph, Karl D</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>ASAIO journal (1992)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Grzegorzewska, Alicja E</au><au>Moore, Harold L</au><au>Chen, Tzen W</au><au>Nolph, Karl D</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Peritoneal Transfer During Maximal Hyperosmotic Ultrafiltration in the Rat</atitle><jtitle>ASAIO journal (1992)</jtitle><addtitle>ASAIO J</addtitle><date>1993-01</date><risdate>1993</risdate><volume>39</volume><issue>1</issue><spage>66</spage><epage>70</epage><pages>66-70</pages><issn>1058-2916</issn><eissn>1538-943X</eissn><coden>AJOUET</coden><abstract>Peritoneal transfer parameters were estimated in rats (n=24) while maximal net ultrafiltration rate (nUFR) was achieved with 15% dextrose dialysis solution (1,153 mOsm/kg) and compared with those obtained with 0.37% dextrose solution (301 mOsm/kg). Experiments were carried out with dialysis solutions of pH ?6.5 and ? 7.6, respectively, for 15% dextrose dialysis solution and 0.37% dextrose solution. Increases in both convective and diffusive transfer resulted in more than 70% greater peritoneal clearances of urea, potassium, and phosphate with hyperosmotic solutions at both pH values. Protein removal was increased only with a hyperosmotic solution of pH ? 6.5 compared with isosmotic conditions at the same pH. Results support the hypothesis that increased peritoneal transfer parameters under hyperosmotic conditions depend not only upon enhanced convection but also on factors promoting diffusive transfer</abstract><cop>Philadelphia, PA</cop><cop>Hagerstown, MD</cop><pub>Lippincott-Raven Publishers</pub><pmid>8439684</pmid><doi>10.1097/00002480-199339010-00015</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | ASAIO journal (1992), 1993-01, Vol.39 (1), p.66-70 |
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| language | eng |
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| source | MEDLINE; Journals@Ovid LWW Legacy Archive; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Journals@Ovid Complete |
| subjects | Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Animals Biological and medical sciences Data Interpretation, Statistical Dialysis Solutions Diffusion Disease Models, Animal Emergency and intensive care: renal failure. Dialysis management Glucose Hydrogen-Ion Concentration Intensive care medicine Male Medical sciences Osmolar Concentration Peritoneal Dialysis Rats Rats, Sprague-Dawley Space life sciences Ultrafiltration |
| title | Peritoneal Transfer During Maximal Hyperosmotic Ultrafiltration in the Rat |
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