Obstructive sleep apnoea is associated with risk factors comprising the metabolic syndrome
ABSTRACT Background and objective: Several features of OSA syndrome suggest that it is a manifestation of the metabolic syndrome (MS). In this study, we investigated the prevalence of the MS among male Japanese patients with OSA, as well as the relationship between OSA in non‐obese patients and com...
Gespeichert in:
| Veröffentlicht in: | Respirology (Carlton, Vic.) Vic.), 2010-10, Vol.15 (7), p.1122-1126 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1126 |
|---|---|
| container_issue | 7 |
| container_start_page | 1122 |
| container_title | Respirology (Carlton, Vic.) |
| container_volume | 15 |
| creator | AKAHOSHI, Toshiki UEMATSU, Akihito AKASHIBA, Tsuneto NAGAOKA, Kenichi KIYOFUJI, Kouji KAWAHARA, Seiji HATTORI, Tomohiro KANEITA, Yoshitaka YOSHIZAWA, Takayuki TAKAHASHI, Noriaki UCHIYAMA, Makoto HASHIMOTO, Shu |
| description | ABSTRACT
Background and objective: Several features of OSA syndrome suggest that it is a manifestation of the metabolic syndrome (MS). In this study, we investigated the prevalence of the MS among male Japanese patients with OSA, as well as the relationship between OSA in non‐obese patients and components of the MS other than obesity (hypertension, dyslipidaemia and glucose intolerance).
Methods: The study included 416 Japanese men who were diagnosed as having OSA by polysomnography. Among these, 101 non‐obese patients were selected and the severity of OSA, as well as the prevalence of hypertension, dyslipidaemia and glucose intolerance, was assessed.
Results: The MS was associated with OSA in 218/416 patients (52.4%). A significant increase in the prevalence of the MS was associated with increased severity of OSA, as categorized according to AHI. In the non‐obese patients with OSA (mean age 57.6 years, BMI 22.7 kg/m2, AHI 34.3 events/h), hypertension, dyslipidaemia and glucose intolerance were identified in 70 (69.3%), 43 (42.6%) and 20 patients (19.8%), respectively. At least two of these factors were identified in 40 patients (39.6%). Non‐obese patients with severe OSA had a significantly higher prevalence of two or more of these factors (33/59 patients, 55.9%).
Conclusions: Although Asians are generally less obese than Caucasians, the prevalence of the MS was high among Japanese patients with OSA, and even among non‐obese patients, OSA was associated with risk factors for the MS.
The prevalence of the metabolic syndrome (MS), as well as the relationship between OSA in non‐obese patients and components of the MS, was assessed in Japanese patients with OSA. Early identification of metabolic risk factors, including hypertension, dyslipidaemia and glucose intolerance, may be beneficial in the clinical management of OSA, especially in non‐obese patients. |
| doi_str_mv | 10.1111/j.1440-1843.2010.01818.x |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_755968915</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>755968915</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4078-abd407bd2df0a40b9af84a1e8353a823a009af7427b4f8a338cac2be888d60d13</originalsourceid><addsrcrecordid>eNqNkEFP3DAQhS1EVSjtX0C-ccrWjp21c0ECRAEJlRZaUXGxJs6keEnWi-0tu_8ep0v33LnM6M2bZ_kjhHI24bk-zyZcSlZwLcWkZFllXHM9We2Q_e1iN8-iFIVSdb1HPsQ4Y4yJilXvyV7JVCm45Pvk4aaJKSxtcn-Qxh5xQWEx9wjURQoxeusgYUtfXHqkwcUn2oFNPkRq_bDIgpv_pukR6YAJGt87S-N63gY_4EfyroM-4qe3fkB-fjn_cXZZXN9cXJ2dXBdWMqULaNrcm7ZsOwaSNTV0WgJHLSoBuhTAWJaULFUjOw1CaAu2bFBr3U5Zy8UBOdrkLoJ_XmJMZnDRYt_DHP0yGlVV9VTXvMpOvXHa4GMM2Jn8gwHC2nBmRrBmZkZ-ZuRnRrDmL1izyqeHb48smwHb7eE_ktlwvDG8uB7X_x1sbs_vvo1jDig2AS4mXG0DIDyZqRKqMvdfL8ypunz4fs9PzS_xCjBul98</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>755968915</pqid></control><display><type>article</type><title>Obstructive sleep apnoea is associated with risk factors comprising the metabolic syndrome</title><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><creator>AKAHOSHI, Toshiki ; UEMATSU, Akihito ; AKASHIBA, Tsuneto ; NAGAOKA, Kenichi ; KIYOFUJI, Kouji ; KAWAHARA, Seiji ; HATTORI, Tomohiro ; KANEITA, Yoshitaka ; YOSHIZAWA, Takayuki ; TAKAHASHI, Noriaki ; UCHIYAMA, Makoto ; HASHIMOTO, Shu</creator><creatorcontrib>AKAHOSHI, Toshiki ; UEMATSU, Akihito ; AKASHIBA, Tsuneto ; NAGAOKA, Kenichi ; KIYOFUJI, Kouji ; KAWAHARA, Seiji ; HATTORI, Tomohiro ; KANEITA, Yoshitaka ; YOSHIZAWA, Takayuki ; TAKAHASHI, Noriaki ; UCHIYAMA, Makoto ; HASHIMOTO, Shu</creatorcontrib><description>ABSTRACT
Background and objective: Several features of OSA syndrome suggest that it is a manifestation of the metabolic syndrome (MS). In this study, we investigated the prevalence of the MS among male Japanese patients with OSA, as well as the relationship between OSA in non‐obese patients and components of the MS other than obesity (hypertension, dyslipidaemia and glucose intolerance).
Methods: The study included 416 Japanese men who were diagnosed as having OSA by polysomnography. Among these, 101 non‐obese patients were selected and the severity of OSA, as well as the prevalence of hypertension, dyslipidaemia and glucose intolerance, was assessed.
Results: The MS was associated with OSA in 218/416 patients (52.4%). A significant increase in the prevalence of the MS was associated with increased severity of OSA, as categorized according to AHI. In the non‐obese patients with OSA (mean age 57.6 years, BMI 22.7 kg/m2, AHI 34.3 events/h), hypertension, dyslipidaemia and glucose intolerance were identified in 70 (69.3%), 43 (42.6%) and 20 patients (19.8%), respectively. At least two of these factors were identified in 40 patients (39.6%). Non‐obese patients with severe OSA had a significantly higher prevalence of two or more of these factors (33/59 patients, 55.9%).
Conclusions: Although Asians are generally less obese than Caucasians, the prevalence of the MS was high among Japanese patients with OSA, and even among non‐obese patients, OSA was associated with risk factors for the MS.
The prevalence of the metabolic syndrome (MS), as well as the relationship between OSA in non‐obese patients and components of the MS, was assessed in Japanese patients with OSA. Early identification of metabolic risk factors, including hypertension, dyslipidaemia and glucose intolerance, may be beneficial in the clinical management of OSA, especially in non‐obese patients.</description><identifier>ISSN: 1323-7799</identifier><identifier>EISSN: 1440-1843</identifier><identifier>DOI: 10.1111/j.1440-1843.2010.01818.x</identifier><identifier>PMID: 20723141</identifier><language>eng</language><publisher>Melbourne, Australia: Blackwell Publishing Asia</publisher><subject>Adult ; Aged ; Asian Continental Ancestry Group - statistics & numerical data ; Comorbidity ; Cross-Sectional Studies ; Dyslipidemias - epidemiology ; Dyslipidemias - etiology ; Glucose Intolerance - epidemiology ; Glucose Intolerance - etiology ; Humans ; Hypertension - epidemiology ; Hypertension - etiology ; hypoxaemia ; insulin resistance ; Japan - epidemiology ; Male ; metabolic syndrome ; Metabolic Syndrome - complications ; Metabolic Syndrome - epidemiology ; Middle Aged ; obesity ; Obesity - epidemiology ; Obesity - etiology ; obstructive sleep apnoea ; Prevalence ; Risk Factors ; Severity of Illness Index ; Sleep Apnea, Obstructive - epidemiology ; Sleep Apnea, Obstructive - etiology</subject><ispartof>Respirology (Carlton, Vic.), 2010-10, Vol.15 (7), p.1122-1126</ispartof><rights>2010 The Authors. Respirology © 2010 Asian Pacific Society of Respirology</rights><rights>2010 The Authors. Respirology © 2010 Asian Pacific Society of Respirology.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4078-abd407bd2df0a40b9af84a1e8353a823a009af7427b4f8a338cac2be888d60d13</citedby><cites>FETCH-LOGICAL-c4078-abd407bd2df0a40b9af84a1e8353a823a009af7427b4f8a338cac2be888d60d13</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fj.1440-1843.2010.01818.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fj.1440-1843.2010.01818.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20723141$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>AKAHOSHI, Toshiki</creatorcontrib><creatorcontrib>UEMATSU, Akihito</creatorcontrib><creatorcontrib>AKASHIBA, Tsuneto</creatorcontrib><creatorcontrib>NAGAOKA, Kenichi</creatorcontrib><creatorcontrib>KIYOFUJI, Kouji</creatorcontrib><creatorcontrib>KAWAHARA, Seiji</creatorcontrib><creatorcontrib>HATTORI, Tomohiro</creatorcontrib><creatorcontrib>KANEITA, Yoshitaka</creatorcontrib><creatorcontrib>YOSHIZAWA, Takayuki</creatorcontrib><creatorcontrib>TAKAHASHI, Noriaki</creatorcontrib><creatorcontrib>UCHIYAMA, Makoto</creatorcontrib><creatorcontrib>HASHIMOTO, Shu</creatorcontrib><title>Obstructive sleep apnoea is associated with risk factors comprising the metabolic syndrome</title><title>Respirology (Carlton, Vic.)</title><addtitle>Respirology</addtitle><description>ABSTRACT
Background and objective: Several features of OSA syndrome suggest that it is a manifestation of the metabolic syndrome (MS). In this study, we investigated the prevalence of the MS among male Japanese patients with OSA, as well as the relationship between OSA in non‐obese patients and components of the MS other than obesity (hypertension, dyslipidaemia and glucose intolerance).
Methods: The study included 416 Japanese men who were diagnosed as having OSA by polysomnography. Among these, 101 non‐obese patients were selected and the severity of OSA, as well as the prevalence of hypertension, dyslipidaemia and glucose intolerance, was assessed.
Results: The MS was associated with OSA in 218/416 patients (52.4%). A significant increase in the prevalence of the MS was associated with increased severity of OSA, as categorized according to AHI. In the non‐obese patients with OSA (mean age 57.6 years, BMI 22.7 kg/m2, AHI 34.3 events/h), hypertension, dyslipidaemia and glucose intolerance were identified in 70 (69.3%), 43 (42.6%) and 20 patients (19.8%), respectively. At least two of these factors were identified in 40 patients (39.6%). Non‐obese patients with severe OSA had a significantly higher prevalence of two or more of these factors (33/59 patients, 55.9%).
Conclusions: Although Asians are generally less obese than Caucasians, the prevalence of the MS was high among Japanese patients with OSA, and even among non‐obese patients, OSA was associated with risk factors for the MS.
The prevalence of the metabolic syndrome (MS), as well as the relationship between OSA in non‐obese patients and components of the MS, was assessed in Japanese patients with OSA. Early identification of metabolic risk factors, including hypertension, dyslipidaemia and glucose intolerance, may be beneficial in the clinical management of OSA, especially in non‐obese patients.</description><subject>Adult</subject><subject>Aged</subject><subject>Asian Continental Ancestry Group - statistics & numerical data</subject><subject>Comorbidity</subject><subject>Cross-Sectional Studies</subject><subject>Dyslipidemias - epidemiology</subject><subject>Dyslipidemias - etiology</subject><subject>Glucose Intolerance - epidemiology</subject><subject>Glucose Intolerance - etiology</subject><subject>Humans</subject><subject>Hypertension - epidemiology</subject><subject>Hypertension - etiology</subject><subject>hypoxaemia</subject><subject>insulin resistance</subject><subject>Japan - epidemiology</subject><subject>Male</subject><subject>metabolic syndrome</subject><subject>Metabolic Syndrome - complications</subject><subject>Metabolic Syndrome - epidemiology</subject><subject>Middle Aged</subject><subject>obesity</subject><subject>Obesity - epidemiology</subject><subject>Obesity - etiology</subject><subject>obstructive sleep apnoea</subject><subject>Prevalence</subject><subject>Risk Factors</subject><subject>Severity of Illness Index</subject><subject>Sleep Apnea, Obstructive - epidemiology</subject><subject>Sleep Apnea, Obstructive - etiology</subject><issn>1323-7799</issn><issn>1440-1843</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkEFP3DAQhS1EVSjtX0C-ccrWjp21c0ECRAEJlRZaUXGxJs6keEnWi-0tu_8ep0v33LnM6M2bZ_kjhHI24bk-zyZcSlZwLcWkZFllXHM9We2Q_e1iN8-iFIVSdb1HPsQ4Y4yJilXvyV7JVCm45Pvk4aaJKSxtcn-Qxh5xQWEx9wjURQoxeusgYUtfXHqkwcUn2oFNPkRq_bDIgpv_pukR6YAJGt87S-N63gY_4EfyroM-4qe3fkB-fjn_cXZZXN9cXJ2dXBdWMqULaNrcm7ZsOwaSNTV0WgJHLSoBuhTAWJaULFUjOw1CaAu2bFBr3U5Zy8UBOdrkLoJ_XmJMZnDRYt_DHP0yGlVV9VTXvMpOvXHa4GMM2Jn8gwHC2nBmRrBmZkZ-ZuRnRrDmL1izyqeHb48smwHb7eE_ktlwvDG8uB7X_x1sbs_vvo1jDig2AS4mXG0DIDyZqRKqMvdfL8ypunz4fs9PzS_xCjBul98</recordid><startdate>201010</startdate><enddate>201010</enddate><creator>AKAHOSHI, Toshiki</creator><creator>UEMATSU, Akihito</creator><creator>AKASHIBA, Tsuneto</creator><creator>NAGAOKA, Kenichi</creator><creator>KIYOFUJI, Kouji</creator><creator>KAWAHARA, Seiji</creator><creator>HATTORI, Tomohiro</creator><creator>KANEITA, Yoshitaka</creator><creator>YOSHIZAWA, Takayuki</creator><creator>TAKAHASHI, Noriaki</creator><creator>UCHIYAMA, Makoto</creator><creator>HASHIMOTO, Shu</creator><general>Blackwell Publishing Asia</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201010</creationdate><title>Obstructive sleep apnoea is associated with risk factors comprising the metabolic syndrome</title><author>AKAHOSHI, Toshiki ; UEMATSU, Akihito ; AKASHIBA, Tsuneto ; NAGAOKA, Kenichi ; KIYOFUJI, Kouji ; KAWAHARA, Seiji ; HATTORI, Tomohiro ; KANEITA, Yoshitaka ; YOSHIZAWA, Takayuki ; TAKAHASHI, Noriaki ; UCHIYAMA, Makoto ; HASHIMOTO, Shu</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4078-abd407bd2df0a40b9af84a1e8353a823a009af7427b4f8a338cac2be888d60d13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Asian Continental Ancestry Group - statistics & numerical data</topic><topic>Comorbidity</topic><topic>Cross-Sectional Studies</topic><topic>Dyslipidemias - epidemiology</topic><topic>Dyslipidemias - etiology</topic><topic>Glucose Intolerance - epidemiology</topic><topic>Glucose Intolerance - etiology</topic><topic>Humans</topic><topic>Hypertension - epidemiology</topic><topic>Hypertension - etiology</topic><topic>hypoxaemia</topic><topic>insulin resistance</topic><topic>Japan - epidemiology</topic><topic>Male</topic><topic>metabolic syndrome</topic><topic>Metabolic Syndrome - complications</topic><topic>Metabolic Syndrome - epidemiology</topic><topic>Middle Aged</topic><topic>obesity</topic><topic>Obesity - epidemiology</topic><topic>Obesity - etiology</topic><topic>obstructive sleep apnoea</topic><topic>Prevalence</topic><topic>Risk Factors</topic><topic>Severity of Illness Index</topic><topic>Sleep Apnea, Obstructive - epidemiology</topic><topic>Sleep Apnea, Obstructive - etiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>AKAHOSHI, Toshiki</creatorcontrib><creatorcontrib>UEMATSU, Akihito</creatorcontrib><creatorcontrib>AKASHIBA, Tsuneto</creatorcontrib><creatorcontrib>NAGAOKA, Kenichi</creatorcontrib><creatorcontrib>KIYOFUJI, Kouji</creatorcontrib><creatorcontrib>KAWAHARA, Seiji</creatorcontrib><creatorcontrib>HATTORI, Tomohiro</creatorcontrib><creatorcontrib>KANEITA, Yoshitaka</creatorcontrib><creatorcontrib>YOSHIZAWA, Takayuki</creatorcontrib><creatorcontrib>TAKAHASHI, Noriaki</creatorcontrib><creatorcontrib>UCHIYAMA, Makoto</creatorcontrib><creatorcontrib>HASHIMOTO, Shu</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Respirology (Carlton, Vic.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>AKAHOSHI, Toshiki</au><au>UEMATSU, Akihito</au><au>AKASHIBA, Tsuneto</au><au>NAGAOKA, Kenichi</au><au>KIYOFUJI, Kouji</au><au>KAWAHARA, Seiji</au><au>HATTORI, Tomohiro</au><au>KANEITA, Yoshitaka</au><au>YOSHIZAWA, Takayuki</au><au>TAKAHASHI, Noriaki</au><au>UCHIYAMA, Makoto</au><au>HASHIMOTO, Shu</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Obstructive sleep apnoea is associated with risk factors comprising the metabolic syndrome</atitle><jtitle>Respirology (Carlton, Vic.)</jtitle><addtitle>Respirology</addtitle><date>2010-10</date><risdate>2010</risdate><volume>15</volume><issue>7</issue><spage>1122</spage><epage>1126</epage><pages>1122-1126</pages><issn>1323-7799</issn><eissn>1440-1843</eissn><abstract>ABSTRACT
Background and objective: Several features of OSA syndrome suggest that it is a manifestation of the metabolic syndrome (MS). In this study, we investigated the prevalence of the MS among male Japanese patients with OSA, as well as the relationship between OSA in non‐obese patients and components of the MS other than obesity (hypertension, dyslipidaemia and glucose intolerance).
Methods: The study included 416 Japanese men who were diagnosed as having OSA by polysomnography. Among these, 101 non‐obese patients were selected and the severity of OSA, as well as the prevalence of hypertension, dyslipidaemia and glucose intolerance, was assessed.
Results: The MS was associated with OSA in 218/416 patients (52.4%). A significant increase in the prevalence of the MS was associated with increased severity of OSA, as categorized according to AHI. In the non‐obese patients with OSA (mean age 57.6 years, BMI 22.7 kg/m2, AHI 34.3 events/h), hypertension, dyslipidaemia and glucose intolerance were identified in 70 (69.3%), 43 (42.6%) and 20 patients (19.8%), respectively. At least two of these factors were identified in 40 patients (39.6%). Non‐obese patients with severe OSA had a significantly higher prevalence of two or more of these factors (33/59 patients, 55.9%).
Conclusions: Although Asians are generally less obese than Caucasians, the prevalence of the MS was high among Japanese patients with OSA, and even among non‐obese patients, OSA was associated with risk factors for the MS.
The prevalence of the metabolic syndrome (MS), as well as the relationship between OSA in non‐obese patients and components of the MS, was assessed in Japanese patients with OSA. Early identification of metabolic risk factors, including hypertension, dyslipidaemia and glucose intolerance, may be beneficial in the clinical management of OSA, especially in non‐obese patients.</abstract><cop>Melbourne, Australia</cop><pub>Blackwell Publishing Asia</pub><pmid>20723141</pmid><doi>10.1111/j.1440-1843.2010.01818.x</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1323-7799 |
| ispartof | Respirology (Carlton, Vic.), 2010-10, Vol.15 (7), p.1122-1126 |
| issn | 1323-7799 1440-1843 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_755968915 |
| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Adult Aged Asian Continental Ancestry Group - statistics & numerical data Comorbidity Cross-Sectional Studies Dyslipidemias - epidemiology Dyslipidemias - etiology Glucose Intolerance - epidemiology Glucose Intolerance - etiology Humans Hypertension - epidemiology Hypertension - etiology hypoxaemia insulin resistance Japan - epidemiology Male metabolic syndrome Metabolic Syndrome - complications Metabolic Syndrome - epidemiology Middle Aged obesity Obesity - epidemiology Obesity - etiology obstructive sleep apnoea Prevalence Risk Factors Severity of Illness Index Sleep Apnea, Obstructive - epidemiology Sleep Apnea, Obstructive - etiology |
| title | Obstructive sleep apnoea is associated with risk factors comprising the metabolic syndrome |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-08T05%3A54%3A29IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Obstructive%20sleep%20apnoea%20is%20associated%20with%20risk%20factors%20comprising%20the%20metabolic%20syndrome&rft.jtitle=Respirology%20(Carlton,%20Vic.)&rft.au=AKAHOSHI,%20Toshiki&rft.date=2010-10&rft.volume=15&rft.issue=7&rft.spage=1122&rft.epage=1126&rft.pages=1122-1126&rft.issn=1323-7799&rft.eissn=1440-1843&rft_id=info:doi/10.1111/j.1440-1843.2010.01818.x&rft_dat=%3Cproquest_cross%3E755968915%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=755968915&rft_id=info:pmid/20723141&rfr_iscdi=true |