Synthesis of new amino acid and peptide derivatives of estradiol and their binding affinities for the estrogen receptor

A series of amino acid and peptide derivatives of estradiol have been synthesized by coupling 17β-aminoestra-1, 3,5(10)-trien-3-ol, 17-hydrazonoestra-1,3,5(10)-trien-3-ol with amino acids or peptides, using tetrahydrothiazole-2-thione, N-hydroxy-1,4-epoxycyclohex-5-ene-2,3-dicarbonylimide, benzotria...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Steroids 1993, Vol.58 (1), p.35-39
Hauptverfasser:	Yun-hua, Ye, Yun-sheng, Huang, Zhi-qing, Wang, Su-ming, Chen, Ying, Tiant
Format:	Artikel
Sprache:	eng
Schlagworte:	17-hydrazonoestrone derivatives 17β-aminoestradiol derivatives amino acids Amino Acids - chemical synthesis Amino Acids - chemistry Amino Acids - metabolism Analytical, structural and metabolic biochemistry Animals binding affinity Binding, Competitive Biological and medical sciences Estradiol - analogs & derivatives Estradiol - chemistry Estradiol - metabolism estrogen receptor Female Fundamental and applied biological sciences. Psychology Indicators and Reagents Magnetic Resonance Spectroscopy Mass Spectrometry Other biological molecules peptides Peptides - chemical synthesis Peptides - chemistry Peptides - metabolism Rats Receptors, Estrogen - metabolism steroids Terpenes, steroids. Hormones Uterus - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!