Late thrombotic obstruction of an aortic bioprosthetic valve: Successful treatment by oral anticoagulation

Thrombotic obstruction of aortic bioprostheses is rare. Few cases have been reported involving the use of the Carpentier‐Edwards (CE) prosthesis, the Hancock bioprosthesis, or the Medtronic Intact porcine valve.1, 4 Thrombolytic therapy for mechanical valve thrombosis has been used frequently even t...

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Veröffentlicht in:Clinical cardiology (Mahwah, N.J.) N.J.), 1993-02, Vol.16 (2), p.152-154
Hauptverfasser: Juliard, Jean‐Michel, Paillole, Catherine, Dahan, Michel, Gabriel Steg, P., Himbert, Dominique, Aumont, Marie‐Claude
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container_end_page 154
container_issue 2
container_start_page 152
container_title Clinical cardiology (Mahwah, N.J.)
container_volume 16
creator Juliard, Jean‐Michel
Paillole, Catherine
Dahan, Michel
Gabriel Steg, P.
Himbert, Dominique
Aumont, Marie‐Claude
description Thrombotic obstruction of aortic bioprostheses is rare. Few cases have been reported involving the use of the Carpentier‐Edwards (CE) prosthesis, the Hancock bioprosthesis, or the Medtronic Intact porcine valve.1, 4 Thrombolytic therapy for mechanical valve thrombosis has been used frequently even though it is known to carry a high risk of embolism and recurrence.5 However, the use of this therapy was reported for the first time only recently,1 in a case of acute aortic thrombosis which occurred 3 1/2 months after bioprosthesis insertion. We report a case of late progressive thrombotic obstruction of a CE aortic valve 3 years after insertion. The case was successfully treated with Coumadin therapy, as confirmed by serial Doppler echocardiographic examinations and a 3‐year follow‐up.
doi_str_mv 10.1002/clc.4960160215
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Few cases have been reported involving the use of the Carpentier‐Edwards (CE) prosthesis, the Hancock bioprosthesis, or the Medtronic Intact porcine valve.1, 4 Thrombolytic therapy for mechanical valve thrombosis has been used frequently even though it is known to carry a high risk of embolism and recurrence.5 However, the use of this therapy was reported for the first time only recently,1 in a case of acute aortic thrombosis which occurred 3 1/2 months after bioprosthesis insertion. We report a case of late progressive thrombotic obstruction of a CE aortic valve 3 years after insertion. 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Few cases have been reported involving the use of the Carpentier‐Edwards (CE) prosthesis, the Hancock bioprosthesis, or the Medtronic Intact porcine valve.1, 4 Thrombolytic therapy for mechanical valve thrombosis has been used frequently even though it is known to carry a high risk of embolism and recurrence.5 However, the use of this therapy was reported for the first time only recently,1 in a case of acute aortic thrombosis which occurred 3 1/2 months after bioprosthesis insertion. We report a case of late progressive thrombotic obstruction of a CE aortic valve 3 years after insertion. 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Few cases have been reported involving the use of the Carpentier‐Edwards (CE) prosthesis, the Hancock bioprosthesis, or the Medtronic Intact porcine valve.1, 4 Thrombolytic therapy for mechanical valve thrombosis has been used frequently even though it is known to carry a high risk of embolism and recurrence.5 However, the use of this therapy was reported for the first time only recently,1 in a case of acute aortic thrombosis which occurred 3 1/2 months after bioprosthesis insertion. We report a case of late progressive thrombotic obstruction of a CE aortic valve 3 years after insertion. The case was successfully treated with Coumadin therapy, as confirmed by serial Doppler echocardiographic examinations and a 3‐year follow‐up.</abstract><cop>New York</cop><pub>Wiley Periodicals, Inc</pub><pmid>8435930</pmid><doi>10.1002/clc.4960160215</doi><tpages>3</tpages></addata></record>
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source MEDLINE; Wiley Online Library Journals Frontfile Complete; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection
subjects anticoagulation therapy
aortic valve
Aortic Valve - diagnostic imaging
Biological and medical sciences
Bioprosthesis
Constriction, Pathologic - drug therapy
Echocardiography, Doppler
Heart Valve Diseases - diagnostic imaging
Heart Valve Diseases - drug therapy
Heart Valve Prosthesis
Humans
Male
Medical sciences
Middle Aged
Prosthesis Failure
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Surgery of the heart
thrombosis
Thrombosis - diagnostic imaging
Thrombosis - drug therapy
Warfarin - therapeutic use
title Late thrombotic obstruction of an aortic bioprosthetic valve: Successful treatment by oral anticoagulation
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