Synthesis of 2'-deoxy-L-fucopyranosylcarminomycinone and -.epsilon.-pyrromycinone as well as 2'-deoxy-D-erythro-pentopyranosyldaunomycinone, -carminomycinone, and -.epsilon.-pyrromycinone

Treatment of di-O-acetyl-2-deoxy-L-fucopyranosyl bromide with carminomycinone and epsilon-pyrromycinone in the presence of mercuric bromide and mercuric cyanide afforded 3',4'-diO-acetyl-2'-deoxy-L-fucopyranosylcarminomycinone and -epsilon-pyrromycinone. Similarly, when di-O-acetyl-2-...

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Veröffentlicht in:	Journal of medicinal chemistry 1981-01, Vol.24 (1), p.112-115
Hauptverfasser:	El Khadem, Hassan S, Swartz, David L
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anthracyclines Antibiotics, Antineoplastic - chemical synthesis Bacteria - drug effects Carubicin - analogs & derivatives Carubicin - chemical synthesis Carubicin - pharmacology Chemical Phenomena Chemistry Mice Naphthacenes - chemical synthesis Naphthacenes - pharmacology
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