Tonsillectomy and adenoidectomy pain reduction by local bupivacaine infiltration in children
Experimental data in humans and animals suggest that during surgery, pain impulses enter the CNS creating a hyperexcitable state in spite of general anesthesia. In a prospective double blind study, pain levels in 22 children undergoing tonsillectomy and adenoidectomy under general anesthesia were co...
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| Veröffentlicht in: | International journal of pediatric otorhinolaryngology 1993, Vol.25 (1), p.149-154 |
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| container_title | International journal of pediatric otorhinolaryngology |
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| creator | Jebeles, John A. Reilly, James S. Gutierrez, Juan F. Bradley, Edwin L. Kissin, Igor |
| description | Experimental data in humans and animals suggest that during surgery, pain impulses enter the CNS creating a hyperexcitable state in spite of general anesthesia. In a prospective double blind study, pain levels in 22 children undergoing tonsillectomy and adenoidectomy under general anesthesia were compared from day of surgery to Day 10. Patients received pre-incisional infiltration with either bupivacaine (A) or saline (B). Subjective pain was assessed by visual analog scale, and objective pain by deglutition time (100 ml). Subjective constant pain was less (
P < 0.05) in group (A) on Day 1: 16 (A) vs. 59 (B) and Day 5: 4 (A) vs. 45 (B). We conclude that local nerve blockade by bupivacaine reduces short- and long-term pain in children undergoing tonsillectomy and adenoidectomy in the presence of general anesthesia. |
| doi_str_mv | 10.1016/0165-5876(93)90048-8 |
| format | Article |
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P < 0.05) in group (A) on Day 1: 16 (A) vs. 59 (B) and Day 5: 4 (A) vs. 45 (B). We conclude that local nerve blockade by bupivacaine reduces short- and long-term pain in children undergoing tonsillectomy and adenoidectomy in the presence of general anesthesia.</description><identifier>ISSN: 0165-5876</identifier><identifier>EISSN: 1872-8464</identifier><identifier>DOI: 10.1016/0165-5876(93)90048-8</identifier><identifier>PMID: 8436459</identifier><identifier>CODEN: IPOTDJ</identifier><language>eng</language><publisher>Amsterdam: Elsevier Ireland Ltd</publisher><subject>Adenoidectomy ; Anesthesia ; Anesthesia, General ; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy ; Biological and medical sciences ; Bupivacaine ; Child ; Double-Blind Method ; Female ; Humans ; Intraoperative Care ; Local anesthesia. Pain (treatment) ; Male ; Medical sciences ; Pain ; Pain management Abstract ; Pain Measurement ; Pain, Postoperative - epidemiology ; Pain, Postoperative - prevention & control ; Prospective Studies ; Sodium Chloride ; Time Factors ; Tonsillectomy</subject><ispartof>International journal of pediatric otorhinolaryngology, 1993, Vol.25 (1), p.149-154</ispartof><rights>1993</rights><rights>1993 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c386t-f9bf206baa6bc23fc0cedc687b065307a673cec94ae3dfef2d0edf3db9be90303</citedby><cites>FETCH-LOGICAL-c386t-f9bf206baa6bc23fc0cedc687b065307a673cec94ae3dfef2d0edf3db9be90303</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/0165587693900488$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,4010,27900,27901,27902,65534</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=4610378$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/8436459$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Jebeles, John A.</creatorcontrib><creatorcontrib>Reilly, James S.</creatorcontrib><creatorcontrib>Gutierrez, Juan F.</creatorcontrib><creatorcontrib>Bradley, Edwin L.</creatorcontrib><creatorcontrib>Kissin, Igor</creatorcontrib><title>Tonsillectomy and adenoidectomy pain reduction by local bupivacaine infiltration in children</title><title>International journal of pediatric otorhinolaryngology</title><addtitle>Int J Pediatr Otorhinolaryngol</addtitle><description>Experimental data in humans and animals suggest that during surgery, pain impulses enter the CNS creating a hyperexcitable state in spite of general anesthesia. In a prospective double blind study, pain levels in 22 children undergoing tonsillectomy and adenoidectomy under general anesthesia were compared from day of surgery to Day 10. Patients received pre-incisional infiltration with either bupivacaine (A) or saline (B). Subjective pain was assessed by visual analog scale, and objective pain by deglutition time (100 ml). Subjective constant pain was less (
P < 0.05) in group (A) on Day 1: 16 (A) vs. 59 (B) and Day 5: 4 (A) vs. 45 (B). We conclude that local nerve blockade by bupivacaine reduces short- and long-term pain in children undergoing tonsillectomy and adenoidectomy in the presence of general anesthesia.</description><subject>Adenoidectomy</subject><subject>Anesthesia</subject><subject>Anesthesia, General</subject><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</subject><subject>Biological and medical sciences</subject><subject>Bupivacaine</subject><subject>Child</subject><subject>Double-Blind Method</subject><subject>Female</subject><subject>Humans</subject><subject>Intraoperative Care</subject><subject>Local anesthesia. Pain (treatment)</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Pain</subject><subject>Pain management Abstract</subject><subject>Pain Measurement</subject><subject>Pain, Postoperative - epidemiology</subject><subject>Pain, Postoperative - prevention & control</subject><subject>Prospective Studies</subject><subject>Sodium Chloride</subject><subject>Time Factors</subject><subject>Tonsillectomy</subject><issn>0165-5876</issn><issn>1872-8464</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1993</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kM1qGzEURkVpcFwnb9DALEJoF5NorJFGsykUk6SBQDbJLiD0c0VVZMmRZgx--8j24GUXQqDv3A_dg9D3Bt82uGF35dCa8o796MnPHuOW1_wLmje8W9a8Ze1XND8h5-hbzv8wbjpM6QzNeEtYS_s5en-NITvvQQ9xvatkMJU0EKIz08tGulAlMKMeXAyV2lU-aukrNW7cVuqSQuWCdX5I8kAUXP913iQIF-jMSp_hcroX6O3h_nX1p35-eXxa_X6uNeFsqG2v7BIzJSVTekmsxhqMZrxTmFGCO8k6okH3rQRiLNilwWAsMapX0GOCyQLdHHs3KX6MkAexdlmD9zJAHLPoKOUNLTsvUHsEdYo5J7Bik9xapp1osNhLFXtjYm9M9EQcpApexq6m_lGtwZyGJoslv55ymYsbm2TQLp-wljWYdPuaX0cMioutgySydhDKsi4V28JE9_9_fAKxyJYB</recordid><startdate>1993</startdate><enddate>1993</enddate><creator>Jebeles, John A.</creator><creator>Reilly, James S.</creator><creator>Gutierrez, Juan F.</creator><creator>Bradley, Edwin L.</creator><creator>Kissin, Igor</creator><general>Elsevier Ireland Ltd</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>8BM</scope></search><sort><creationdate>1993</creationdate><title>Tonsillectomy and adenoidectomy pain reduction by local bupivacaine infiltration in children</title><author>Jebeles, John A. ; Reilly, James S. ; Gutierrez, Juan F. ; Bradley, Edwin L. ; Kissin, Igor</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c386t-f9bf206baa6bc23fc0cedc687b065307a673cec94ae3dfef2d0edf3db9be90303</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1993</creationdate><topic>Adenoidectomy</topic><topic>Anesthesia</topic><topic>Anesthesia, General</topic><topic>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</topic><topic>Biological and medical sciences</topic><topic>Bupivacaine</topic><topic>Child</topic><topic>Double-Blind Method</topic><topic>Female</topic><topic>Humans</topic><topic>Intraoperative Care</topic><topic>Local anesthesia. Pain (treatment)</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Pain</topic><topic>Pain management Abstract</topic><topic>Pain Measurement</topic><topic>Pain, Postoperative - epidemiology</topic><topic>Pain, Postoperative - prevention & control</topic><topic>Prospective Studies</topic><topic>Sodium Chloride</topic><topic>Time Factors</topic><topic>Tonsillectomy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Jebeles, John A.</creatorcontrib><creatorcontrib>Reilly, James S.</creatorcontrib><creatorcontrib>Gutierrez, Juan F.</creatorcontrib><creatorcontrib>Bradley, Edwin L.</creatorcontrib><creatorcontrib>Kissin, Igor</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>ComDisDome</collection><jtitle>International journal of pediatric otorhinolaryngology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Jebeles, John A.</au><au>Reilly, James S.</au><au>Gutierrez, Juan F.</au><au>Bradley, Edwin L.</au><au>Kissin, Igor</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Tonsillectomy and adenoidectomy pain reduction by local bupivacaine infiltration in children</atitle><jtitle>International journal of pediatric otorhinolaryngology</jtitle><addtitle>Int J Pediatr Otorhinolaryngol</addtitle><date>1993</date><risdate>1993</risdate><volume>25</volume><issue>1</issue><spage>149</spage><epage>154</epage><pages>149-154</pages><issn>0165-5876</issn><eissn>1872-8464</eissn><coden>IPOTDJ</coden><abstract>Experimental data in humans and animals suggest that during surgery, pain impulses enter the CNS creating a hyperexcitable state in spite of general anesthesia. 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P < 0.05) in group (A) on Day 1: 16 (A) vs. 59 (B) and Day 5: 4 (A) vs. 45 (B). We conclude that local nerve blockade by bupivacaine reduces short- and long-term pain in children undergoing tonsillectomy and adenoidectomy in the presence of general anesthesia.</abstract><cop>Amsterdam</cop><pub>Elsevier Ireland Ltd</pub><pmid>8436459</pmid><doi>10.1016/0165-5876(93)90048-8</doi><tpages>6</tpages></addata></record> |
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| subjects | Adenoidectomy Anesthesia Anesthesia, General Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Bupivacaine Child Double-Blind Method Female Humans Intraoperative Care Local anesthesia. Pain (treatment) Male Medical sciences Pain Pain management Abstract Pain Measurement Pain, Postoperative - epidemiology Pain, Postoperative - prevention & control Prospective Studies Sodium Chloride Time Factors Tonsillectomy |
| title | Tonsillectomy and adenoidectomy pain reduction by local bupivacaine infiltration in children |
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