NMR studies of phospholipase C hydrolysis of phosphatidylcholine in model membranes

Hydrolysis of phospholipids in biological membranes by phospholipase C (PLC) produces an important second messenger molecule, 1,2-diacylglycerol (DAG), that is essential for the activation of protein kinase C (PKC). While the effects of DAG on model membranes have been investigated earlier, studies...

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Veröffentlicht in:	The Journal of biological chemistry 1993-02, Vol.268 (4), p.2431-2434
Hauptverfasser:	BHAMIDIPATI, S. P, HAMILTON, J. A
Format:	Artikel
Sprache:	eng
Schlagworte:	activity Biological and medical sciences Cell physiology Diglycerides - metabolism Fundamental and applied biological sciences. Psychology hydrolysis In Vitro Techniques Lipid Bilayers Magnetic Resonance Spectroscopy Membranes, Artificial Molecular and cellular biology N.M.R phosphatidylcholine Phosphatidylcholines - metabolism phospholipase C Signal transduction Type C Phospholipases - metabolism vesicles
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