Lung Cancer in Patients With Immunodeficiency Syndrome
We report adenocarcinoma of the lung in seven patients with human immunodeficiency virus (HIV) infection. We compared age, clinical findings and survival data with a sex-matched control group of HIV-negative patients with adenocarcînoma of the lung. Median age of HIV-infected patients with lung canc...
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| Veröffentlicht in: | Chest 1993-02, Vol.103 (2), p.410-413 |
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| container_title | Chest |
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| creator | Karp, Jason Profeta, George Marantz, Paul R. Karpel, Jill P. |
| description | We report adenocarcinoma of the lung in seven patients with human immunodeficiency virus (HIV) infection. We compared age, clinical findings and survival data with a sex-matched control group of HIV-negative patients with adenocarcînoma of the lung. Median age of HIV-infected patients with lung cancer was lower than in control patients with lung cancer. The HIV-infected patients had more systemic symptoms and abnormal physical findings than control subjects. Both groups had smoking histories. Laboratory data were similar but control subjects had lower blood oxygen tensions than did HIV patients; HIV patients had more abnormalities on chest roentgenograms and computed tomography scans than did control subjects. All HIV-infected patients were stage IV. Median survival was 4 weeks. For control patients, 50 percent had stage IV disease; median survival was 25.5 weeks. Thus, patients with HIV infection develop lung cancer at a younger age than sex-matched control subjects and undergo a more fulminant course with shortened survivals. |
| doi_str_mv | 10.1378/chest.103.2.410 |
| format | Article |
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We compared age, clinical findings and survival data with a sex-matched control group of HIV-negative patients with adenocarcînoma of the lung. Median age of HIV-infected patients with lung cancer was lower than in control patients with lung cancer. The HIV-infected patients had more systemic symptoms and abnormal physical findings than control subjects. Both groups had smoking histories. Laboratory data were similar but control subjects had lower blood oxygen tensions than did HIV patients; HIV patients had more abnormalities on chest roentgenograms and computed tomography scans than did control subjects. All HIV-infected patients were stage IV. Median survival was 4 weeks. For control patients, 50 percent had stage IV disease; median survival was 25.5 weeks. Thus, patients with HIV infection develop lung cancer at a younger age than sex-matched control subjects and undergo a more fulminant course with shortened survivals.</description><identifier>ISSN: 0012-3692</identifier><identifier>EISSN: 1931-3543</identifier><identifier>DOI: 10.1378/chest.103.2.410</identifier><identifier>PMID: 8432128</identifier><identifier>CODEN: CHETBF</identifier><language>eng</language><publisher>Northbrook, IL: Elsevier Inc</publisher><subject>Acquired Immunodeficiency Syndrome - complications ; Adenocarcinoma - complications ; Adenocarcinoma - mortality ; Adenocarcinoma - pathology ; Adult ; Aged ; AIDS/HIV ; Biological and medical sciences ; Female ; human immunodeficiency virus ; Humans ; Immunodeficiencies ; Immunodeficiencies. Immunoglobulinopathies ; Immunopathology ; Lung Neoplasms - complications ; Lung Neoplasms - mortality ; Lung Neoplasms - pathology ; Male ; Medical sciences ; Middle Aged ; Retrospective Studies ; Survival Rate</subject><ispartof>Chest, 1993-02, Vol.103 (2), p.410-413</ispartof><rights>1993 The American College of Chest Physicians</rights><rights>1993 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c442t-e0267a6a604ef0b4ef12a5fabcbf8190471d87a4cade2ee7a793b6df8dc3dbc73</citedby><cites>FETCH-LOGICAL-c442t-e0267a6a604ef0b4ef12a5fabcbf8190471d87a4cade2ee7a793b6df8dc3dbc73</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=4663080$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/8432128$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Karp, Jason</creatorcontrib><creatorcontrib>Profeta, George</creatorcontrib><creatorcontrib>Marantz, Paul R.</creatorcontrib><creatorcontrib>Karpel, Jill P.</creatorcontrib><title>Lung Cancer in Patients With Immunodeficiency Syndrome</title><title>Chest</title><addtitle>Chest</addtitle><description>We report adenocarcinoma of the lung in seven patients with human immunodeficiency virus (HIV) infection. We compared age, clinical findings and survival data with a sex-matched control group of HIV-negative patients with adenocarcînoma of the lung. Median age of HIV-infected patients with lung cancer was lower than in control patients with lung cancer. The HIV-infected patients had more systemic symptoms and abnormal physical findings than control subjects. Both groups had smoking histories. Laboratory data were similar but control subjects had lower blood oxygen tensions than did HIV patients; HIV patients had more abnormalities on chest roentgenograms and computed tomography scans than did control subjects. All HIV-infected patients were stage IV. Median survival was 4 weeks. For control patients, 50 percent had stage IV disease; median survival was 25.5 weeks. Thus, patients with HIV infection develop lung cancer at a younger age than sex-matched control subjects and undergo a more fulminant course with shortened survivals.</description><subject>Acquired Immunodeficiency Syndrome - complications</subject><subject>Adenocarcinoma - complications</subject><subject>Adenocarcinoma - mortality</subject><subject>Adenocarcinoma - pathology</subject><subject>Adult</subject><subject>Aged</subject><subject>AIDS/HIV</subject><subject>Biological and medical sciences</subject><subject>Female</subject><subject>human immunodeficiency virus</subject><subject>Humans</subject><subject>Immunodeficiencies</subject><subject>Immunodeficiencies. Immunoglobulinopathies</subject><subject>Immunopathology</subject><subject>Lung Neoplasms - complications</subject><subject>Lung Neoplasms - mortality</subject><subject>Lung Neoplasms - pathology</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Retrospective Studies</subject><subject>Survival Rate</subject><issn>0012-3692</issn><issn>1931-3543</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1993</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkUtLxDAUhYMoOj7WroQuxF3HvJqkSxl8wYCCisuQJrdOpA9NWmX-vdEZ1I24Sbi555ybfEHokOApYVKd2gXEYUowm9IpJ3gDTUjJSM4KzjbRBGNCcyZKuoN2Y3zGqSal2EbbijNKqJogMR-7p2xmOgsh8112awYP3RCzRz8ssuu2HbveQe1tOrXL7G7ZudC3sI-2atNEOFjve-jh4vx-dpXPby6vZ2fz3HJOhxwwFdIIIzCHGldpIdQUtalsVStSYi6JU9JwaxxQAGlkySrhauUsc5WVbA-drHJfQv86pqfq1kcLTWM66MeoZVFIWSTXf0IiFC04VUl4uhLa0McYoNYvwbcmLDXB-hOp_kKaKqapTkiT42gdPVYtuG_9mmHqH6_7JlrT1CHB9PFbxoVgWOGfwQv_tHj3AXRsTdOkULYa-dyPoTPN78HlygGJ8JuHoOPXN4BLbjto1_s_L_0BhMqkGQ</recordid><startdate>19930201</startdate><enddate>19930201</enddate><creator>Karp, Jason</creator><creator>Profeta, George</creator><creator>Marantz, Paul R.</creator><creator>Karpel, Jill P.</creator><general>Elsevier Inc</general><general>American College of Chest Physicians</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7U9</scope><scope>H94</scope><scope>7X8</scope></search><sort><creationdate>19930201</creationdate><title>Lung Cancer in Patients With Immunodeficiency Syndrome</title><author>Karp, Jason ; Profeta, George ; Marantz, Paul R. ; Karpel, Jill P.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c442t-e0267a6a604ef0b4ef12a5fabcbf8190471d87a4cade2ee7a793b6df8dc3dbc73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1993</creationdate><topic>Acquired Immunodeficiency Syndrome - complications</topic><topic>Adenocarcinoma - complications</topic><topic>Adenocarcinoma - mortality</topic><topic>Adenocarcinoma - pathology</topic><topic>Adult</topic><topic>Aged</topic><topic>AIDS/HIV</topic><topic>Biological and medical sciences</topic><topic>Female</topic><topic>human immunodeficiency virus</topic><topic>Humans</topic><topic>Immunodeficiencies</topic><topic>Immunodeficiencies. Immunoglobulinopathies</topic><topic>Immunopathology</topic><topic>Lung Neoplasms - complications</topic><topic>Lung Neoplasms - mortality</topic><topic>Lung Neoplasms - pathology</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Retrospective Studies</topic><topic>Survival Rate</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Karp, Jason</creatorcontrib><creatorcontrib>Profeta, George</creatorcontrib><creatorcontrib>Marantz, Paul R.</creatorcontrib><creatorcontrib>Karpel, Jill P.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Chest</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Karp, Jason</au><au>Profeta, George</au><au>Marantz, Paul R.</au><au>Karpel, Jill P.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Lung Cancer in Patients With Immunodeficiency Syndrome</atitle><jtitle>Chest</jtitle><addtitle>Chest</addtitle><date>1993-02-01</date><risdate>1993</risdate><volume>103</volume><issue>2</issue><spage>410</spage><epage>413</epage><pages>410-413</pages><issn>0012-3692</issn><eissn>1931-3543</eissn><coden>CHETBF</coden><abstract>We report adenocarcinoma of the lung in seven patients with human immunodeficiency virus (HIV) infection. We compared age, clinical findings and survival data with a sex-matched control group of HIV-negative patients with adenocarcînoma of the lung. Median age of HIV-infected patients with lung cancer was lower than in control patients with lung cancer. The HIV-infected patients had more systemic symptoms and abnormal physical findings than control subjects. Both groups had smoking histories. Laboratory data were similar but control subjects had lower blood oxygen tensions than did HIV patients; HIV patients had more abnormalities on chest roentgenograms and computed tomography scans than did control subjects. All HIV-infected patients were stage IV. Median survival was 4 weeks. For control patients, 50 percent had stage IV disease; median survival was 25.5 weeks. Thus, patients with HIV infection develop lung cancer at a younger age than sex-matched control subjects and undergo a more fulminant course with shortened survivals.</abstract><cop>Northbrook, IL</cop><pub>Elsevier Inc</pub><pmid>8432128</pmid><doi>10.1378/chest.103.2.410</doi><tpages>4</tpages></addata></record> |
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| ispartof | Chest, 1993-02, Vol.103 (2), p.410-413 |
| issn | 0012-3692 1931-3543 |
| language | eng |
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| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Acquired Immunodeficiency Syndrome - complications Adenocarcinoma - complications Adenocarcinoma - mortality Adenocarcinoma - pathology Adult Aged AIDS/HIV Biological and medical sciences Female human immunodeficiency virus Humans Immunodeficiencies Immunodeficiencies. Immunoglobulinopathies Immunopathology Lung Neoplasms - complications Lung Neoplasms - mortality Lung Neoplasms - pathology Male Medical sciences Middle Aged Retrospective Studies Survival Rate |
| title | Lung Cancer in Patients With Immunodeficiency Syndrome |
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