Effect of chronic intake of dietary fibers on the ultrastructural topography of rat jejunum and colon: a scanning electron microscopy study
This report is an attempt to quantitate the observable topographical characteristics of small and large intestine after a specific dietary regimen under well-defined states of lipid absorption and metabolism. Alfalfa, white wheat bran, cellulose, and pectin were fed for 6 wk at a level of 15 g/100 g...
Gespeichert in:
| Veröffentlicht in: | The American journal of clinical nutrition 1981-02, Vol.34 (2), p.218-228 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 228 |
|---|---|
| container_issue | 2 |
| container_start_page | 218 |
| container_title | The American journal of clinical nutrition |
| container_volume | 34 |
| creator | Cassidy, M M Lightfoot, F G Grau, L E Story, J A Kritchevsky, D Vahouny, G V |
| description | This report is an attempt to quantitate the observable topographical characteristics of small and large intestine after a specific dietary regimen under well-defined states of lipid absorption and metabolism. Alfalfa, white wheat bran, cellulose, and pectin were fed for 6 wk at a level of 15 g/100 g diet to four groups of rats (12 rats per dietary group). A 5th control group was maintained on Purina Rat Chow. Three animals from each group were blind-coded for morphological assessment. After anesthesia, the jejunum and mid-colon were removed and processed for scanning electron microscopy. Beginning with the mildest mucosal surface changes, the observed order in terms of increasing severity is bran < cellulose < pectin < alfalfa. Our observations suggest that altered rates of cell loss in intestinal tract cytokinetics may be occurring with particular feeding patterns and should be considered as a possible mechanism in the nutritional consequences of dietary fiber intake. |
| doi_str_mv | 10.1093/ajcn/34.2.218 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_75576061</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0002916523427931</els_id><sourcerecordid>75576061</sourcerecordid><originalsourceid>FETCH-LOGICAL-c441t-60d62f3cc0ce69891710a40d1e89cc96c87200a74e781de48ae1bcc47ef1e76f3</originalsourceid><addsrcrecordid>eNp1kE9v1DAQxS1EVZbCkSOST9yytZ2snXBDVVuQKnEpZ8s7nnS9JHbwH6T9DHxpHO2KG6eRZt68N_Mj5ANnW86G9tYcwd-23VZsBe9fkQ0f2r5pBVOvyYYxJpqBy90b8jalI2NcdL28JtdS7IZBsA35cz-OCJmGkcIhBu-AOp_NT1w71mE28URHt8eYaPA0H5CWKUeTciyQSzQTzWEJL9Esh9O6E02mRzwWX2ZqvKUQpuA_U0MTGO-df6E41cAaRWcHMSQIy4mmXOzpHbkazZTw_aXekB8P9893X5un74_f7r48NdB1PDeSWSnGFoAByqEfuOLMdMxy7AeAQUKvBGNGdah6brHrDfI9QKdw5Kjk2N6QT2ffJYZfBVPWs0uA02Q8hpK02u2UZJJXYXMWrnemiKNeopsrEc2ZXuHrFb5uOy10hV_1Hy_GZT-j_ae-0K5zdZ5j_e63w6gTOPSA1sXKRNvg_uP8F2VRlrc</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>75576061</pqid></control><display><type>article</type><title>Effect of chronic intake of dietary fibers on the ultrastructural topography of rat jejunum and colon: a scanning electron microscopy study</title><source>MEDLINE</source><source>Alma/SFX Local Collection</source><creator>Cassidy, M M ; Lightfoot, F G ; Grau, L E ; Story, J A ; Kritchevsky, D ; Vahouny, G V</creator><creatorcontrib>Cassidy, M M ; Lightfoot, F G ; Grau, L E ; Story, J A ; Kritchevsky, D ; Vahouny, G V</creatorcontrib><description>This report is an attempt to quantitate the observable topographical characteristics of small and large intestine after a specific dietary regimen under well-defined states of lipid absorption and metabolism. Alfalfa, white wheat bran, cellulose, and pectin were fed for 6 wk at a level of 15 g/100 g diet to four groups of rats (12 rats per dietary group). A 5th control group was maintained on Purina Rat Chow. Three animals from each group were blind-coded for morphological assessment. After anesthesia, the jejunum and mid-colon were removed and processed for scanning electron microscopy. Beginning with the mildest mucosal surface changes, the observed order in terms of increasing severity is bran < cellulose < pectin < alfalfa. Our observations suggest that altered rates of cell loss in intestinal tract cytokinetics may be occurring with particular feeding patterns and should be considered as a possible mechanism in the nutritional consequences of dietary fiber intake.</description><identifier>ISSN: 0002-9165</identifier><identifier>EISSN: 1938-3207</identifier><identifier>DOI: 10.1093/ajcn/34.2.218</identifier><identifier>PMID: 6259920</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>alfalfa ; Animals ; bran ; cellulose ; Cellulose - pharmacology ; Colon - drug effects ; Colon - ultrastructure ; Dietary fiber ; Dietary Fiber - pharmacology ; Intestinal Mucosa - ultrastructure ; intestine ; Jejunum - drug effects ; Jejunum - ultrastructure ; Male ; Medicago sativa ; Microscopy, Electron, Scanning ; Microvilli - ultrastructure ; mucosal surface ; pectin ; Pectins - pharmacology ; Rats ; scanning microscopy ; Triticum</subject><ispartof>The American journal of clinical nutrition, 1981-02, Vol.34 (2), p.218-228</ispartof><rights>1981 American Society for Nutrition.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c441t-60d62f3cc0ce69891710a40d1e89cc96c87200a74e781de48ae1bcc47ef1e76f3</citedby><cites>FETCH-LOGICAL-c441t-60d62f3cc0ce69891710a40d1e89cc96c87200a74e781de48ae1bcc47ef1e76f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,781,785,27929,27930</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6259920$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Cassidy, M M</creatorcontrib><creatorcontrib>Lightfoot, F G</creatorcontrib><creatorcontrib>Grau, L E</creatorcontrib><creatorcontrib>Story, J A</creatorcontrib><creatorcontrib>Kritchevsky, D</creatorcontrib><creatorcontrib>Vahouny, G V</creatorcontrib><title>Effect of chronic intake of dietary fibers on the ultrastructural topography of rat jejunum and colon: a scanning electron microscopy study</title><title>The American journal of clinical nutrition</title><addtitle>Am J Clin Nutr</addtitle><description>This report is an attempt to quantitate the observable topographical characteristics of small and large intestine after a specific dietary regimen under well-defined states of lipid absorption and metabolism. Alfalfa, white wheat bran, cellulose, and pectin were fed for 6 wk at a level of 15 g/100 g diet to four groups of rats (12 rats per dietary group). A 5th control group was maintained on Purina Rat Chow. Three animals from each group were blind-coded for morphological assessment. After anesthesia, the jejunum and mid-colon were removed and processed for scanning electron microscopy. Beginning with the mildest mucosal surface changes, the observed order in terms of increasing severity is bran < cellulose < pectin < alfalfa. Our observations suggest that altered rates of cell loss in intestinal tract cytokinetics may be occurring with particular feeding patterns and should be considered as a possible mechanism in the nutritional consequences of dietary fiber intake.</description><subject>alfalfa</subject><subject>Animals</subject><subject>bran</subject><subject>cellulose</subject><subject>Cellulose - pharmacology</subject><subject>Colon - drug effects</subject><subject>Colon - ultrastructure</subject><subject>Dietary fiber</subject><subject>Dietary Fiber - pharmacology</subject><subject>Intestinal Mucosa - ultrastructure</subject><subject>intestine</subject><subject>Jejunum - drug effects</subject><subject>Jejunum - ultrastructure</subject><subject>Male</subject><subject>Medicago sativa</subject><subject>Microscopy, Electron, Scanning</subject><subject>Microvilli - ultrastructure</subject><subject>mucosal surface</subject><subject>pectin</subject><subject>Pectins - pharmacology</subject><subject>Rats</subject><subject>scanning microscopy</subject><subject>Triticum</subject><issn>0002-9165</issn><issn>1938-3207</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1981</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kE9v1DAQxS1EVZbCkSOST9yytZ2snXBDVVuQKnEpZ8s7nnS9JHbwH6T9DHxpHO2KG6eRZt68N_Mj5ANnW86G9tYcwd-23VZsBe9fkQ0f2r5pBVOvyYYxJpqBy90b8jalI2NcdL28JtdS7IZBsA35cz-OCJmGkcIhBu-AOp_NT1w71mE28URHt8eYaPA0H5CWKUeTciyQSzQTzWEJL9Esh9O6E02mRzwWX2ZqvKUQpuA_U0MTGO-df6E41cAaRWcHMSQIy4mmXOzpHbkazZTw_aXekB8P9893X5un74_f7r48NdB1PDeSWSnGFoAByqEfuOLMdMxy7AeAQUKvBGNGdah6brHrDfI9QKdw5Kjk2N6QT2ffJYZfBVPWs0uA02Q8hpK02u2UZJJXYXMWrnemiKNeopsrEc2ZXuHrFb5uOy10hV_1Hy_GZT-j_ae-0K5zdZ5j_e63w6gTOPSA1sXKRNvg_uP8F2VRlrc</recordid><startdate>198102</startdate><enddate>198102</enddate><creator>Cassidy, M M</creator><creator>Lightfoot, F G</creator><creator>Grau, L E</creator><creator>Story, J A</creator><creator>Kritchevsky, D</creator><creator>Vahouny, G V</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>198102</creationdate><title>Effect of chronic intake of dietary fibers on the ultrastructural topography of rat jejunum and colon: a scanning electron microscopy study</title><author>Cassidy, M M ; Lightfoot, F G ; Grau, L E ; Story, J A ; Kritchevsky, D ; Vahouny, G V</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c441t-60d62f3cc0ce69891710a40d1e89cc96c87200a74e781de48ae1bcc47ef1e76f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1981</creationdate><topic>alfalfa</topic><topic>Animals</topic><topic>bran</topic><topic>cellulose</topic><topic>Cellulose - pharmacology</topic><topic>Colon - drug effects</topic><topic>Colon - ultrastructure</topic><topic>Dietary fiber</topic><topic>Dietary Fiber - pharmacology</topic><topic>Intestinal Mucosa - ultrastructure</topic><topic>intestine</topic><topic>Jejunum - drug effects</topic><topic>Jejunum - ultrastructure</topic><topic>Male</topic><topic>Medicago sativa</topic><topic>Microscopy, Electron, Scanning</topic><topic>Microvilli - ultrastructure</topic><topic>mucosal surface</topic><topic>pectin</topic><topic>Pectins - pharmacology</topic><topic>Rats</topic><topic>scanning microscopy</topic><topic>Triticum</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Cassidy, M M</creatorcontrib><creatorcontrib>Lightfoot, F G</creatorcontrib><creatorcontrib>Grau, L E</creatorcontrib><creatorcontrib>Story, J A</creatorcontrib><creatorcontrib>Kritchevsky, D</creatorcontrib><creatorcontrib>Vahouny, G V</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The American journal of clinical nutrition</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Cassidy, M M</au><au>Lightfoot, F G</au><au>Grau, L E</au><au>Story, J A</au><au>Kritchevsky, D</au><au>Vahouny, G V</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effect of chronic intake of dietary fibers on the ultrastructural topography of rat jejunum and colon: a scanning electron microscopy study</atitle><jtitle>The American journal of clinical nutrition</jtitle><addtitle>Am J Clin Nutr</addtitle><date>1981-02</date><risdate>1981</risdate><volume>34</volume><issue>2</issue><spage>218</spage><epage>228</epage><pages>218-228</pages><issn>0002-9165</issn><eissn>1938-3207</eissn><abstract>This report is an attempt to quantitate the observable topographical characteristics of small and large intestine after a specific dietary regimen under well-defined states of lipid absorption and metabolism. Alfalfa, white wheat bran, cellulose, and pectin were fed for 6 wk at a level of 15 g/100 g diet to four groups of rats (12 rats per dietary group). A 5th control group was maintained on Purina Rat Chow. Three animals from each group were blind-coded for morphological assessment. After anesthesia, the jejunum and mid-colon were removed and processed for scanning electron microscopy. Beginning with the mildest mucosal surface changes, the observed order in terms of increasing severity is bran < cellulose < pectin < alfalfa. Our observations suggest that altered rates of cell loss in intestinal tract cytokinetics may be occurring with particular feeding patterns and should be considered as a possible mechanism in the nutritional consequences of dietary fiber intake.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>6259920</pmid><doi>10.1093/ajcn/34.2.218</doi><tpages>11</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0002-9165 |
| ispartof | The American journal of clinical nutrition, 1981-02, Vol.34 (2), p.218-228 |
| issn | 0002-9165 1938-3207 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_75576061 |
| source | MEDLINE; Alma/SFX Local Collection |
| subjects | alfalfa Animals bran cellulose Cellulose - pharmacology Colon - drug effects Colon - ultrastructure Dietary fiber Dietary Fiber - pharmacology Intestinal Mucosa - ultrastructure intestine Jejunum - drug effects Jejunum - ultrastructure Male Medicago sativa Microscopy, Electron, Scanning Microvilli - ultrastructure mucosal surface pectin Pectins - pharmacology Rats scanning microscopy Triticum |
| title | Effect of chronic intake of dietary fibers on the ultrastructural topography of rat jejunum and colon: a scanning electron microscopy study |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-10T15%3A07%3A26IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Effect%20of%20chronic%20intake%20of%20dietary%20fibers%20on%20the%20ultrastructural%20topography%20of%20rat%20jejunum%20and%20colon:%20a%20scanning%20electron%20microscopy%20study&rft.jtitle=The%20American%20journal%20of%20clinical%20nutrition&rft.au=Cassidy,%20M%20M&rft.date=1981-02&rft.volume=34&rft.issue=2&rft.spage=218&rft.epage=228&rft.pages=218-228&rft.issn=0002-9165&rft.eissn=1938-3207&rft_id=info:doi/10.1093/ajcn/34.2.218&rft_dat=%3Cproquest_cross%3E75576061%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=75576061&rft_id=info:pmid/6259920&rft_els_id=S0002916523427931&rfr_iscdi=true |