Virological and Immunological Studies in Patients with Acute Viral Hepatitis

One hundred and seven patients with acute viral hepatitis (AVH) were studied prospectively regarding the viral aetiological agent HAV, HBV and NANB (by exclusion) using radioimmunoassay. Acute HAV infection occurred in 43 patients, and acute HBV infection in 34 patients, while HDS occurred in two pa...

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Veröffentlicht in:Scandinavian journal of immunology 1993-02, Vol.37 (2), p.265-270
Hauptverfasser: MARCUS, S., AL‐MOSLIH, M., AL‐TAWIL, N. G., KASSIR, Z. A.
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container_end_page 270
container_issue 2
container_start_page 265
container_title Scandinavian journal of immunology
container_volume 37
creator MARCUS, S.
AL‐MOSLIH, M.
AL‐TAWIL, N. G.
KASSIR, Z. A.
description One hundred and seven patients with acute viral hepatitis (AVH) were studied prospectively regarding the viral aetiological agent HAV, HBV and NANB (by exclusion) using radioimmunoassay. Acute HAV infection occurred in 43 patients, and acute HBV infection in 34 patients, while HDS occurred in two patients only. Acute, presumably NANB, infection occurred in 28 patients. Ten out of 28 sera of patients with AHBV infection were positive for smooth muscle antibody by immunofluorescence. Important findings include: (1) presence of delta superinfection in the absence of HBsAg; (2) HBsAg as the only marker in two patients with AHBV infection; (3) concurrent presence of HBsAg and anti‐HBsAg in three patients with AHBV infection.
doi_str_mv 10.1111/j.1365-3083.1993.tb01765.x
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A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Virological and Immunological Studies in Patients with Acute Viral Hepatitis</atitle><jtitle>Scandinavian journal of immunology</jtitle><addtitle>Scand J Immunol</addtitle><date>1993-02</date><risdate>1993</risdate><volume>37</volume><issue>2</issue><spage>265</spage><epage>270</epage><pages>265-270</pages><issn>0300-9475</issn><eissn>1365-3083</eissn><coden>SJIMAX</coden><abstract>One hundred and seven patients with acute viral hepatitis (AVH) were studied prospectively regarding the viral aetiological agent HAV, HBV and NANB (by exclusion) using radioimmunoassay. Acute HAV infection occurred in 43 patients, and acute HBV infection in 34 patients, while HDS occurred in two patients only. Acute, presumably NANB, infection occurred in 28 patients. Ten out of 28 sera of patients with AHBV infection were positive for smooth muscle antibody by immunofluorescence. Important findings include: (1) presence of delta superinfection in the absence of HBsAg; (2) HBsAg as the only marker in two patients with AHBV infection; (3) concurrent presence of HBsAg and anti‐HBsAg in three patients with AHBV infection.</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><pmid>8434238</pmid><doi>10.1111/j.1365-3083.1993.tb01765.x</doi><tpages>6</tpages></addata></record>
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source MEDLINE; Wiley Online Library Journals Frontfile Complete
subjects Acute Disease
Adolescent
Adult
Aged
Antibodies - classification
Biological and medical sciences
Child
Child, Preschool
Female
hepatitis A virus
Hepatitis Antibodies - blood
Hepatitis B - epidemiology
Hepatitis B - immunology
hepatitis B virus
hepatitis C virus
hepatitis D virus
Hepatitis Viruses - isolation & purification
Hepatitis, Viral, Human - immunology
Hepatitis, Viral, Human - microbiology
Human viral diseases
Humans
Immunoglobulins - classification
Infant
Infectious diseases
Male
Medical sciences
Middle Aged
Muscle, Smooth - immunology
Viral diseases
Viral hepatitis
title Virological and Immunological Studies in Patients with Acute Viral Hepatitis
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