Alkylamides as inducers of human leukemia cell differentiation : a quantitative structure-activity relationship study using comparative molecular field analysis

Computer assisted quantitative structure-activity studies using comparative molecular field analysis (CoMFA) were performed on a series of alkylamides that induce cell differentiation. The series included alkylformamides, alkylacetamides, alkylureas, and substituted hexyl analogues of acetamide. The...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 1993-02, Vol.53 (4), p.766-771
Hauptverfasser:	HARPALANI, A. D, SNYDER, S. W, SUBRAMANYAM, B, EGORIN, M. J, CALLERY, P. S
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic agents Biological and medical sciences Cell Differentiation - drug effects Computer Graphics General aspects Humans Least-Squares Analysis Leukemia, Promyelocytic, Acute - pathology Medical sciences Oligopeptides - chemistry Oligopeptides - pharmacology Pharmacology. Drug treatments Structure-Activity Relationship Tumor Cells, Cultured
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