In vitro studies to investigate the reasons for the low potency of cholestyramine and colestipol

The association rates, dissociation rates, and equilibrium binding of bile acids with cholestyramine and colestipol were measured under physiological conditions with the most abundant bile acids found in humans. Cholestyramine and colestipol equilibrated with the bile acids (5 mM) within 1 h and the...

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Veröffentlicht in:	Journal of pharmaceutical sciences 1993-01, Vol.82 (1), p.80-86
Hauptverfasser:	Martin Benson, G., Haynes, Claire, Blanchard, Stephen, Ellis, David
Format:	Artikel
Sprache:	eng
Schlagworte:	Bile - chemistry Bile Acids and Salts - chemistry Biological and medical sciences Cholestyramine Resin - chemistry Colestipol - chemistry General and cellular metabolism. Vitamins Medical sciences Pharmacology. Drug treatments Solubility
Online-Zugang:	Volltext
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