Therapeutic Trial of Lipid X in a Canine Model of Septic Shock

Three groups of dogs were given lipid X (0, 1, or 10 mg/kg) every 8 h for sevendoses, starting simultaneously with the intraperitoneal placement of Escherichia coli-containing fibrin clots. All animals developed bacteremia, hypotension, and a pattern of decreased left ventricular ejection fraction c...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Journal of infectious diseases 1993-02, Vol.167 (2), p.378-384
Hauptverfasser:	Danner, Robert L., Eichacker, Peter Q., Doerfler, Martin E., Hoffman, William D., Reilly, Joseph M., Wilson, James, MacVittie, Thomas J., Stuetz, Peter, Parrillo, Joseph E., Natanson, Charles
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal models Animals Antibiotics. Antiinfectious agents. Antiparasitic agents Bacteremia Biological and medical sciences Canines Disease Models, Animal Dogs Dosage Dose-Response Relationship, Drug Endotoxemia Endotoxins Escherichia coli Escherichia coli Infections - drug therapy Escherichia coli Infections - physiopathology Glycolipids - administration & dosage Glycolipids - therapeutic use Hemodynamics Infections Leukocyte Count Lipids Major Articles Medical sciences Medical treatment Miscellaneous. Antibiotics with multiple activities Pharmacology. Drug treatments Random Allocation Septic shock Shock, Septic - drug therapy Shock, Septic - physiopathology Treatment Outcome
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!