Day/night differences in D1 but not D2 DA receptor protection from EEDQ denaturation in rats treated with continuous cocaine

The effect of chronic cocaine administration on the in vivo occupation of dopamine (DA) receptor subtypes was examined using the irreversible receptor blocker N‐ethoxycarbonyl‐2‐ethoxy‐1, 2‐dihydroquinoline (EEDQ). Rats were given continuous infusions of cocaine (vehicle, 2.5, 7.5, or 22.5 mg/day) v...

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Veröffentlicht in:	Synapse (New York, N.Y.) N.Y.), 1993-01, Vol.13 (1), p.20-29
Hauptverfasser:	Burger, Lynn Y., Martin-Iverson, Mathew T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenergic alpha-Antagonists - pharmacology Animals Benzazepines - pharmacology Circadian Rhythm - physiology Circadian rhythms Cocaine - pharmacology Dopamine D2 Receptor Antagonists Ligands Male Phasic DA Quinolines - pharmacology Raclopride Rats Rats, Sprague-Dawley Receptors, Dopamine D1 - drug effects Receptors, Dopamine D2 - drug effects Salicylamides - pharmacology SCH 23390 Striatum
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