The Effect of Pulmonary Impairment on All-Cause Mortality in a National Cohort

The association between pulmonary impairment and all-cause mortality was investigated among white subjects in a follow-up study of a large national cohort. Pulmonary function was measured during the National Health and Nutrition Examination Survey (NHANESI) (1971 to 1975); subsequent mortality infor...

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Veröffentlicht in:Chest 1993-02, Vol.103 (2), p.536-540
Hauptverfasser: Bang, Ki Moon, Gergen, Peter J., Kramer, Rachel, Cohen, Bruce
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container_title Chest
container_volume 103
creator Bang, Ki Moon
Gergen, Peter J.
Kramer, Rachel
Cohen, Bruce
description The association between pulmonary impairment and all-cause mortality was investigated among white subjects in a follow-up study of a large national cohort. Pulmonary function was measured during the National Health and Nutrition Examination Survey (NHANESI) (1971 to 1975); subsequent mortality information was obtained from the 1987 NHANES I Epidemiologic Follow-up Study (1982 to 1987). Of 4,764 white sample persons, ages 25 to 74 years examined during NHANES I, 658 (13.8 percent) were identified as having pulmonary impairment defined as a FEV1/FVC ≤69 percent. A total of 743 (15.6 percent) sample persons died during the follow-up period. The association between pulmonary impairment and all-cause mortality was examined for male and female subjects separately using the Cox proportional hazards model controlling for age, smoking, educational level, body mass index, and respiratory diseases. The analysis suggests that reduced FEV1 percent predicted was a significant risk factor for mortality among both sexes, and the FEV1/FVC ratio was significantly associated with all-cause mortality among male subjects only.
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subjects Adult
Aged
Analysis. Health state
Biological and medical sciences
Cohort Studies
Epidemiology
Female
Forced Expiratory Volume
General aspects
Humans
Male
Medical sciences
Middle Aged
Mortality
Public health. Hygiene
Public health. Hygiene-occupational medicine
Risk Factors
Sex Factors
Smoking
United States - epidemiology
Vital Capacity
title The Effect of Pulmonary Impairment on All-Cause Mortality in a National Cohort
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