Inhaled nitric oxide in congenital heart disease

Congenital heart lesions may be complicated by pulmonary arterial smooth muscle hyperplasia, hypertrophy, and hypertension. We assessed whether inhaling low levels of nitric oxide (NO), an endothelium-derived relaxing factor, would produce selective pulmonary vasodilation in pediatric patients with...

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Veröffentlicht in:	Circulation (New York, N.Y.) N.Y.), 1993-02, Vol.87 (2), p.447-453
Hauptverfasser:	ROBERTS, J. D, LANG, P, BIGATELLO, L. M, VLAHAKES, G. J, ZAPOL, W. M
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Inhalation Biological and medical sciences Cardiac Catheterization Cardiology. Vascular system Child Child, Preschool Congenital heart diseases. Malformations of the aorta, pulmonary vessels and vena cava Dose-Response Relationship, Drug Heart Heart Defects, Congenital - complications Heart Defects, Congenital - physiopathology Hemodynamics - drug effects Humans Hypertension, Pulmonary - complications Infant Medical sciences Nitric Oxide - administration & dosage Nitric Oxide - pharmacology Oxygen - administration & dosage Oxygen - pharmacology Pulmonary Circulation - drug effects Vasoconstriction - drug effects Vasodilator Agents - pharmacology
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