Naloxone stimulates comparable release of luteinizing hormone-releasing hormone from tissue fragments from ovariectomized, estrogen-treated young and middle-aged female rats

Endogenous opioids play a role in the regulation of LH-RH neurosecretion throughout the estrous cycle and during the preovulatory LH surge on proestrus. Experimental evidence suggests that opioid influence may be altered with age, and it has been hypothesized that these alterations may contribute to...

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Veröffentlicht in:	Brain research 1993-01, Vol.601 (1), p.246-254
1. Verfasser:	Rubin, Beverly S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging - metabolism Aging Superfusion Animals Biological and medical sciences Endogenous oipioid Estradiol - pharmacology Estrogens - pharmacology Estrous cyclicity Estrus - physiology Female Fundamental and applied biological sciences. Psychology Gonadotropin-releasing hormone Gonadotropin-Releasing Hormone - blood Hormones and neuropeptides. Regulation Hypothalamus - drug effects Hypothalamus - metabolism Hypothalamus. Hypophysis. Epiphysis. Urophysis In Vitro Techniques Luteinizing hormone Luteinizing Hormone - blood Luteinizing Hormone - metabolism Luteinizing hormone-releasing hormone Naloxone Naloxone - pharmacology Norepinephrine - pharmacology Ovariectomy Potassium Chloride - pharmacology Pregnancy Radioimmunoassay Rats Rats, Sprague-Dawley Stimulation, Chemical Vertebrates: endocrinology
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