Interferon induction by 5-halo-6-phenyl pyrimidinones

The interferon inducing characteristics of a new series of 6-phenyl pyrimidinol compounds are described and compared against a previously identified pyrimidine, 2-amino-5-bromo-6-methyl-4-pyrimidinol (ABMP). Interestingly, a split in ability to induce interferon but not in vivo antiviral activity wa...

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Veröffentlicht in:	Journal of interferon research 1980, Vol.1 (1), p.1-14
Hauptverfasser:	Stringfellow, D A, Vanderberg, H C, Weed, S D
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antiviral Agents - pharmacology Cats Cattle Cells, Cultured Cytosine - analogs & derivatives Cytosine - pharmacology Encephalomyocarditis virus - growth & development Female Fibroblasts Humans Hydrocarbons, Halogenated - pharmacology Interferon Inducers L Cells (Cell Line) Mice Mice, Inbred ICR Pyrimidines - pharmacology Pyrimidinones - pharmacology Semliki forest virus - growth & development Vesicular stomatitis Indiana virus - growth & development
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