Blockade of endogenous opiates reduces activity in the rat

Naloxone (2 mg/kg, SC) was found to result in a substantial and significant reduction in general activity levels in the rat (90–120 days old). This effect was seen both under baseline conditions and after stress manipulations which would be expected to result in elevated levels of endogenous opiate...

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Veröffentlicht in:	Pharmacology, biochemistry and behavior biochemistry and behavior, 1981, Vol.14 (1), p.113-116
Hauptverfasser:	Michael Walker, J., Berntson, Gary G., Paulucci, Thomas S., Champney, Timothy C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Depression, Chemical Endorphins Endorphins - antagonists & inhibitors Female Male Motor Activity - drug effects Naloxone Naloxone - pharmacology Rats Stress Swimming Temperature Time Factors
Online-Zugang:	Volltext
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