Effect of dermorphin on behavior and hippocampal electrical activity in rabbits

Dermorphin, a naturally occurring heptapeptide that selectively binds to μ-opioid receptors, was injected intravenously 0.4 mg/kg in male rabbits. Eight days before injection the spontaneous behavior of the animals was observed in a neutral environment in the absence of external stimuli. At the same...

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Veröffentlicht in:	Life sciences (1973) 1993, Vol.52 (3), p.323-328
Hauptverfasser:	Fontani, G., Vergnani, L., Salvadori, S., Voglino, N., Aloisi, A.M., Portaluppi, F., degli Uberti, E.C.
Format:	Artikel
Sprache:	eng
Schlagworte:	activity Analgesics, Opioid - administration & dosage Analgesics, Opioid - pharmacology Animals Behavior, Animal - drug effects behaviour Biological and medical sciences dermorphin EEG effects on Electrophysiology hippocampus Hippocampus - drug effects Hippocampus - physiology Injections, Intravenous Male Medical sciences Neuropharmacology Neurotransmitters. Neurotransmission. Receptors Oligopeptides - administration & dosage Oligopeptides - pharmacology opiates Opioid Peptides Peptidergic system (neuropeptide, opioid peptide, opiates...). Adenosinergic and purinergic systems Pharmacology. Drug treatments Rabbits receptors
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