Time until definitive quality of life score deterioration as a means of longitudinal analysis for treatment trials in patients with metastatic pancreatic adenocarcinoma

Abstract Background The Fédération Francophone de Cancérologie Digestive phase III trial in patients with metastatic pancreatic adenocarcinoma comparing 5FU, folinic acid and cisplatin combination followed by gemcitabine (Arm A) versus the opposite sequence (Arm B) failed to demonstrate a benefit in...

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Veröffentlicht in:	European journal of cancer (1990) 2010-10, Vol.46 (15), p.2753-2762
Hauptverfasser:	Bonnetain, Franck, Dahan, Laetitia, Maillard, Emilie, Ychou, Marc, Mitry, Emmanuel, Hammel, Pascal, Legoux, Jean-Louis, Rougier, Philippe, Bedenne, Laurent, Seitz, Jean-François
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - drug therapy Adenocarcinoma - mortality Adenocarcinoma - psychology Antineoplastic Combined Chemotherapy Protocols - therapeutic use Biological and medical sciences Chemotherapy Emotions Fatigue - etiology Female Hematology, Oncology and Palliative Medicine Humans Kaplan-Meier Estimate Longitudinal Studies Male Medical sciences Methodology Neoplasm Metastasis Pain - etiology Pancreatic cancer Pancreatic Neoplasms - drug therapy Pancreatic Neoplasms - mortality Pancreatic Neoplasms - psychology Pharmacology. Drug treatments Quality of Life Surrogate end-point Surveys and Questionnaires Time Factors Tumors
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